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Linking disease processes to pharmacological interventions, Clinical Pharmacology for Prescribing gives a sound basis for evidence based prescribing.
Until about a decade ago, the non-coding part of the genome was considered without function. RNA sequencing studies have shown, however, that a considerable part of the non-coding genome is transcribed and that these non-coding RNAs (nc-RNAs) can regulate gene expression. Almost on weekly basis, new findings reveal the regulatory role of nc-RNAs exert in many biological processes. Overall, these studies are making increasingly clear that, both in model organisms and in humans, complexity is not a function of the number of protein-coding genes, but results from the possibility of using combinations of genetic programs and controlling their spatial and temporal regulation during development, s...
Un compromiso con la vida Acompañar la trayectoria de vida de Marcos Carámbula es una invitación a recorrer buena parte de la historia reciente de nuestro país. Desde su infancia en la ciudad de Las Piedras, con su efervescente clima cultural y político durante los años cincuenta, pasando por una juventud dedicada a la acción social, la reflexión espiritual, el compromiso político y la lucha contra la desigualdad, sus elecciones personales lo condujeron por diferentes caminos. Solidario vocacional, su responsabilidad para con el prójimo lo impulsó a la carrera de Medicina, a la gestión de instituciones deportivas, y también a la política, en medio de los tormentosos años de la...
This book adopts a novel patient-centred approach to introduce drug action at the cellular and molecular level while developing clinical topics in the context of individual patients and their experience of illness. In so doing, it takes the important step of relating the scientific basis of pharmacology to real-life pharmacy practice.
This book is a collection of classical as well as innovative methods used to investigate axon degeneration with a particular focus on addressing the common challenges encountered while performing these procedures. Particular attention is devoted to the study of axon loss in several model organisms, as each poses unique challenges and provides powerful advantages. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Axon Degeneration: Methods and Protocols is an ideal guide for facilitating the application and further development of these protocols, which will help the scientific community tackle important questions regarding axon degeneration. Chapters 2, 3, and 20 are available Open Access under a Creative Commons Attribution 4.0 International License via link.springer.com.
The oxford textbook of paediatric pain brings together clinicians, educators, trainees and researchers to provide an authoritative resource on all aspects of pain in infants, children and youth.
Now in its twelfth edition, Lewin's GENES continues to lead with new information and cutting-edge developments, covering gene structure, sequencing, organization, and expression. Leading scientists provide revisions and updates in their individual field of study offering readers current data and information on the rapidly changing subjects in molecular biology.
Pathophysiology and Pharmacology in Nursing provides an integrated introduction to both the biology of disease and the therapeutic agents that are used to manage them.