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Epileptic Seizure Disorders in Animal Models: Advances in Translational Approaches
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The Brain as a Tool
There are two distinct views about the functions of our brains and their origins. The standard view, taught in most neuroscience texts, has incoming messages about the world sent to the cerebral cortex, with the cortex then producing an appropriate motor output. The interactive view, largely expressed by philosophers and psychologists, stresses the continuous sensorimotor interactions of the brain with the world. The Brain as a Tool focuses on thalamo-cortical interactions on the basis of the interactive view, exploring the phylogenetically new transthalamic corticocortical pathways of mammals that link a hierarchy of cortical areas to each other and back to the phylogenetically older motor ...
Astrocytic Synaptic Plasticity in Epilepsy: From Synapses to Circuits
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Women and the City, Women in the City
An attempt to reveal, recover and reconsider the roles, positions, and actions of Ottoman women, this volume reconsiders the negotiations, alliances, and agency of women in asserting themselves in the public domain in late- and post-Ottoman cities. Drawing on diverse theoretical backgrounds and a variety of source materials, from court records to memoirs to interviews, the contributors to the volume reconstruct the lives of these women within the urban sphere. With a fairly wide geographical span, from Aleppo to Sofia, from Jeddah to Istanbul, the chapters offer a wide panorama of the Ottoman urban geography, with a specific concern for gender roles.
IgG4 Autoantibodies in the Context of IgG4 Autoimmunity
Many autoimmune diseases are induced by pathogenic autoantibodies, that bind to self-antigen expressed in cells and tissues, and induce disease by the recruitment of immune cells, activation of the classical complement pathway or induction of antigen cross-linking and endocytosis. These pathogenic mechanisms are, however, not available to antibodies of the IgG4 subclass, as these differ structurally from the other IgG subclasses, leaving them “immunologically inert”. In general, it is thought that IgG4 is part of an anti-inflammatory immune response to an overreactive pro-inflammatory response, e.g. in the context of helminth infection and allergy.
Kindling 6
Proceedings of the Sixth International Conference on Kindling, featuring valuable summaries of the participants’ current cutting-edge research on the kindling of seizures and related phenomena in epilepsy.
Women and Slavery in the Late Ottoman Empire
This book examines gender politics through slavery and social regulation in the Ottoman Empire during the eighteenth and nineteenth centuries.
Experimental Models of Epilepsy and Related Comorbidities
Epileptic patients live with epilepsy-associated complications such as cognitive dysfunction, psychological discomfort, and sexual function decline, and are more likely to experience emotional and mental health issues problems, including depression and anxiety. Many antiepileptic drugs are found to have a role in aggravating psychiatric symptoms. Animal models, which inform translational questions about epilepsy comorbidities, are used to study the relationship between epilepsy and related comorbidities. The aim of this Research Topic was to highlight basic, clinical and interdisciplinary research involved in studying the disease and its comorbid effects. Various experimental models are used to understand the mechansims of disease and to discover newer antiepileptic drugs. These experimental models combines the input from behavioral, biochemical and molecular level including genetic.
Chemical-induced Seizures
"Since the Tokyo Sarin Subway Attack, the threat of chemical warfare agents has migrated from the battlefield to become a major concern for homeland security in the 21th century. While current fielded antidotes are able to mitigate acute high mortality ari"
Anti-Veiling Campaigns in the Muslim World
In recent years bitter controversies have erupted across Europe and the Middle East about women’s veiling, and especially their wearing of the face-veil or niqab. Yet the deeper issues contained within these controversies – secularism versus religious belief, individual freedom versus social or family coercion, identity versus integration – are not new but are strikingly prefigured by earlier conflicts. This book examines the state-sponsored anti-veiling campaigns which swept across wide swathes of the Muslim world in the interwar period, especially in Turkey and the Balkans, Iran, Afghanistan and the Soviet republics of the Caucasus and Central Asia. It shows how veiling was officially discouraged and ridiculed as backward and, although it was rarely banned, veiling was politicized and turned into a rallying-point for a wider opposition. Asking a number of questions about this earlier anti-veiling discourse and the policies flowing from it, and the reactions which it provoked, the book illuminates and contextualizes contemporary debates about gender, Islam and modernism.
