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Learn to improve your assessment, investigation, and management of physical health conditions in people with severe mental illness The Maudsley Practice Guidelines for Physical Health Conditions in Psychiatry offers psychiatric and general practitioners an evidence-based and practical guide for the appropriate assessment, investigation, and management of common physical health conditions seen in people with severe mental illness. Written by a renowned team of respected experts in medicine, surgery, pharmacy, dietetics, physiotherapy, and psychiatry, the book bridges the gap between psychiatric and physical health services for the severely mentally ill. The Maudsley Practice Guidelines for Ph...
This revised and updated edition of Care of the Mentally Disordered Offender in the Community provides a comprehensive, evidence-based guide to theory and practice. The social and clinical context within which mental health care is provided to offenders in community settings has changed significantly in recent years. An increasing proportion of all mental health care is provided in the community and our knowledge of the links between violence and mental illness has advanced. Existing psychological and pharmacological treatments have been refined and new treatments have been introduced. Epidemiological and intervention-based research has evaluated these changes and suggested new avenues for c...
All natural auditory signals, including human speech and animal communication signals, are spectrally and temporally complex, that is, they contain multiple frequencies and their frequency composition, or spectrum, varies over time. The ability of hearers to identify and localize these signals depends on analysis of their spectral composition. For the overwhelming majority of human listeners spoken language is the major means of social communication, and this communication therefore depends on spectral analysis. Spectral analysis begins in the cochlea, but is then elaborated at various stages along the auditory pathways in the brain that lead from the cochlea to the cerebral cortex. The broa...
The serotonin 5-HT6 receptor represents a novel pharmacological target whose impact on physiopathology of CNS functions remains undetermined. Some receptor antagonists have been synthesized and they show a modulatory role in learning and memory processes and food intake. The pharmacology of 5-HT6 receptor agonists is still under evaluation. However, both 5-HT6 antagonists and agonists seem to exert potential antidepressant activity. Recently, a second messenger system has been discovered. 5-HT6 receptor function is becoming more and more intriguing. Thus, the aim of the present book is to try to clarify the pharmacology of 5-HT6 receptors. - Written by expert researchers - Covers all published literature to date in the field of 5-HT6 receptors
In this volume, members of the International Translational Research Network on Orofacial Neurological Disorders and invited experts provide authoritative overviews of new aspects of motor function and sensation relating to neurological disorders in orofacial regions. Orofacial movements constitute fundamental motor patterns with essential roles in consummatory behavior, self-care, defensive and attack behaviors, vocalization and, in higher mammals, verbal as well as non-verbal communication. Clinically, dysfunction in orofacial movement is evident in numerous dental, cranio-maxillo-facial and neuropsychiatric disorders, including dysphagia, Huntington's disease, Parkinson's disease and schizophrenia. - Leading authors review state-of-the-art in their field of investigation and provide their views and perspectives for future research - Chapters are extensively referenced to provide readers with a comprehensive list of resources on the topics covered - All chapters include comprehensive background information and are written in a clear form that is also accessible to the non-specialist
Volume 95 of International Review of Neurobiology focuses on Catechol-O-methyltransferase inhibition, and its clinical application in relation to Parkinson's disease. Chapters cover COMT gene and proteins, L-dopa treatment in Parkinson's disease, the latest research on COMT inhibitors and their clinical applications, as well as future prospects for their use. - Up-to-date summary of biochemistry and pharmacology of COMT and its inhibitors - Preclinical models in COMT inhibitor devlopment - Transgenic COMT mice – latest information summarized - Chemistry of COMT inhibitors and their design with molecular modelling - COMT gene and its regulation and relation to dopamine related diseases - Role of cofactor SAM regulation in relation to homocysteine - Nonclinical and clinical safety of COMT inhibitors summarized - Future prospects of COMT inhibitors in Parkinson's disease
With recent advances of modern medicine, more people reach the "elderly age around the globe, and the number of dementia cases are ever increasing. This book is about various aspects of dementia and provides its readers with a wide range of thought-provoking sub-topics in the field of dementia. The ultimate goal of this monograph is to stimulate other physicians' and neuroscientists' interest to carry out more research projects into the pathogenesis of this devastating group of diseases.
The fully updated 12th edition of an essential reference for anyone responsible for prescribing drugs for patients with mental health disorders. A well-respected and widely-used source of information on which drugs to prescribe, which side effects to look out for, how best to augment or switch drugs, and more Provides concise reviews of psychiatric disorders and relevant psychopharmacology, along with general guidance based on the data reviewed and current clinical practice Includes specific guidance for schizophrenia, bipolar disorder, depression, anxiety, substance abuse, and special populations such as children, the elderly and pregnant women Each section features a full reference list so the evidence base can be checked quickly and easily This title is also available as a mobile App from MedHand Mobile Libraries. Buy it now from iTunes, Google Play or the MedHand Store.
Interest in the study of peripheral nerve repair and regeneration has increased significantly over the last twenty years and today the number of nerve reconstructions performed is progressively increasing due to the continuous improvement in surgical technology and to the spread of microsurgical skills among surgeons worldwide. This volume of International Review of Neurobiology providdes an overview of the state of the art knowledge in peripheral nerve repair and regeneration by bringing together a number of reviews that critically address some the most important issues in this biomedical field.
A free ebook version of this title is available through Luminos, University of California Press’s Open Access publishing program. Visit www.luminosoa.org to learn more. Unprecedented numbers of young people are in crisis today, and our health care systems are set up to fail them. Breaking Points explores the stories of a diverse group of American young adults experiencing psychiatric hospitalization for psychotic symptoms for the first time and documents how patients and their families make decisions about treatment after their release. Approximately half of young people refuse mental-health care after their initial hospitalization even though we know that better outcomes depend on early support for youth and families. In attempting to determine why this is the case, Neely Laurenzo Myers identifies what matters most to young people in crisis, passionately arguing that health care providers must attend not only to the medical and material dimensions of care but also to a patient's moral agency.