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The Mad Sad Happy Book
From the Author: I'm a child psychologist in Manhattan. One of my goals in my practice is to help children identify emotions in themselves and others. If a young child is able to do this, he or she is better able to make and keep friends, forming bonds that help them weather the inevitable storms of adolescence and beyond. In fact, leading researchers have determined that being emotionally literate not only improves a child's emotional well-being, but also improves a child's academic performance. This book is designed to foster social and emotional intelligence in your child. The first part of the book teaches different emotions, demonstrating them in the faces of the featured children. Your child is then encouraged to identify these emotions in themselves. Ask your child, when prompted, what makes them feel angry or sad, scared or happy. The answers may surprise you. Finally, a game is included that asks your child to identify the different emotions they learned, guessing with only a small part of the face revealed.
Proton Pump Inhibitors
Inhibition of the proton pump in the parietal cells has been established as the main therapeutic principle in the treatment of acid-related diseases, such as peptic ulcer and gastro-oesophageal reflux. The proton pump inhi bitors are tailored for their purpose. They accumulate in the target cell, are activated by acid and bind strongly to the specific target - the proton pump. The clinical superiority of the proton pump inhibitors is due not only to their high efficacy but also to the long duration of the acid inhibition in comparison with other antisecretory drugs. At present when drug discovery mostly relies on identification and characterization of potential targets by genome research, molecular biology, combinatorial chemistry and automated screening, it seems worthwhile to present the development of the tITst proton pump inhibitor - omeprazol- starting from a chemical structure with an observed antisecretory effect but also severe toxic effects that had to be eliminated. As always, basic and applied research operate luind in hand to optimize the delicate balance be tween efficacy and safety of a new drug. This goal often involves time and many different specialists.
The Humboldt Current
A masterly and beautifully written account of the impact of Alexander von Humboldt on nineteenth-century American history and culture The naturalist and explorer Alexander von Humboldt (1769-1859) achieved unparalleled fame in his own time. Today, however, he and his enormous legacy to American thought are virtually unknown. In The Humboldt Current, Aaron Sachs traces Humboldt's pervasive influence on American history through examining the work of four explorers—J. N. Reynolds, Clarence King, George Wallace, and John Muir—who embraced Humboldt's idea of a "chain of connection" uniting all peoples and all environments. A skillful blend of narrative and interpretation that also discusses Humboldt's influence on Emerson, Whitman, Thoreau, Melville, and Poe, The Humboldt Current offers a colorful, passionate, and superbly written reinterpretation of nineteenth-century American history.
Fracture Research in Retrospect
This book describes the historical development of the engineering discipline of fracture mechanics from early times to the scientific treatment of the subject in the 20th century. Most papaers do not require a mathematical background to understand them.
Membrane Physiology
Membrane Physiology is a soft-cover book containing portions of Physiology of Membrane Disorders, published in larger, hard-cover form in 1978. The parent volume was divided into five parts, described in detail in the Preface to the hard-cover edition, which is reproduced in this volume. The present version of Membrane Physiology incorporates the first three of these parts, including a section on the Nature of Biological Membranes, a section on Methods for Studying Membranes, and a section on General Problems in Membrane Biology. It is the hope of the Editors that this smaller volume will be of value to individuals interested in general physiology, the methods for studying general physiology...
What Happened to Goldman Sachs
This is the story of the slow evolution of Goldman Sachs—addressing why and how the firm changed from an ethical standard to a legal one as it grew to be a leading global corporation. In What Happened to Goldman Sachs, Steven G. Mandis uncovers the forces behind what he calls Goldman’s “organizational drift.” Drawing from his firsthand experience; sociological research; analysis of SEC, congressional, and other filings; and a wide array of interviews with former clients, detractors, and current and former partners, Mandis uncovers the pressures that forced Goldman to slowly drift away from the very principles on which its reputation was built. Mandis evaluates what made Goldman Sachs...
Manhattan, the Army and the Atomic Bomb
The role of the War Department, Manhattan District, and other Army agencies and individuals from 1939 through World War II in developing and employing the atomic bomb.
