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Testicular Cancer: New Insights on the Origin, Genetics, Treatment, Fertility, General Health, Quality of Life and Sexual Function
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Understanding the Crosstalk Between Immune Cells and the Tumor Microenvironment in Cancer and Its Implications for Immunotherapy
One of the current challenges and failures of immunotherapy is in part due to the complex tumor microenvironment (TME) that provides a formidable barrier to immune infiltration and function. The TME consists of various cell types (tumor cells, fibroblasts, endothelial cells, and immune cells), soluble signaling molecules (cytokines, growth factors, and chemokines), and extracellular matrix. On another note, metabolic disturbances in various TME components, such as hypoxia, acidosis, lactate accumulation, and nutrient deprivation, can play a critical role in the tumor progression. Furthermore, genetic and epigenetic dysfunctions are known to be part of the characteristics of cancer development. The immune cells could have a pro- or anti-tumor role in the TME, and their activity might vary in the context of different cancers. Both innate and adaptive immune cells interact with tumor cells through direct contact or through chemokines and cytokines signaling, shaping the tumor's activity and response to therapy.
Genetic and proteomic biomarkers in solid tumor detection and treatment
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Pattern Recognition. ICPR International Workshops and Challenges
This 8-volumes set constitutes the refereed of the 25th International Conference on Pattern Recognition Workshops, ICPR 2020, held virtually in Milan, Italy and rescheduled to January 10 - 11, 2021 due to Covid-19 pandemic. The 416 full papers presented in these 8 volumes were carefully reviewed and selected from about 700 submissions. The 46 workshops cover a wide range of areas including machine learning, pattern analysis, healthcare, human behavior, environment, surveillance, forensics and biometrics, robotics and egovision, cultural heritage and document analysis, retrieval, and women at ICPR2020.
Frontiers in Oncology: Quarterly Highlights. Quarter 2 2019
Foreword from the Editor: With the second installment in the Quarterly Highlights series, Frontiers in Oncology has once again had a strong quarter, and continues to publish important research, with submissions from across the globe - and readership from across the globe. In this quarter, we saw a number of different impact metrics become updated using recent data. The 2019 impact metrics reflect our competitive and respectable status in the field and amongst competitors. We find it very encouraging to see that our impact has remained high, and thank the entirety of the Editorial Board and Office for their contributions and hard work in doing so. Once again with a record-breaking number of p...
Almanacco per le provincie dell' i[mperiale] r[egio] governo di Venezia
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