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Biological traits and diseases tend to be very complex. Time is an aspect that deserves particular attention to study and decipher biological traits and disease mechanisms: many processes including biological rhythms, neurodevelopmental and neurodegenerative mechanisms, and aging have a time-dependent trajectory. Biological rhythms, such as circadian rhythms are a reflection of biological processes over 24 hours. In the case of developmental and aging processes, they reflect biological activities over a much longer time scale, typically across years or even decades. In recent years these research fields have been cross-fertilizing each other. Examples include apparent alterations of circadia...
The last decade has witnessed a rapid surge of interest in new sensing and monitoring devices for wellbeing and healthcare. One key development in this area is wireless, wearable and implantable in vivo monitoring and intervention. A myriad of platforms are now available from both academic institutions and commercial organisations. They permit the management of patients with both acute and chronic symptoms, including diabetes, cardiovascular diseases, treatment of epilepsy and other debilitating neurological disorders. Despite extensive developments in sensing technologies, there are significant research issues related to system integration, sensor miniaturisation, low-power sensor interface...
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This Research Topic is part of the Insights in Frontiers in Genetics series. Other titles in the series are: Genetics, Insights in Evolutionary and Population Genetics: 2022 Genetics, Insights in Livestock Genomics: 2022 Genetics, Insights in Epigenomics and Epigenetics: 2022 Genetics, Insights in Behavioral and Psychiatric Genetics: 2022 Genetics, Insights in Neurogenomics: 2022 Genetics, Insights in Genomic Assay Technology: 2022 Genetics, Insights in Genetics of Common and Rare Diseases: 2022 We are now entering the third decade of the 21st Century, and, especially in the last years, the achievements made by scientists have been exceptional, leading to major advancements in the fast-growi...
The struggles between the Immortal, Devil, and Mortal Realms have been endless since time immemorial. The shadows of the sword and Light Sword stained the clothes with blood. Fight for the world! Hunting absolute beauties! To overturn the Heavenly Dao! Only I am! It was a fantasy, a war between all the beings of the three realms. It was a military battle, a war on the battlefield, a war against each other. It was history. Han Xin! A loud name made everyone's blood boil. Behind him, there were even Liu Bang, Xiang Yu, the two prodigies, Zhang Liang, Princess Yu, and Xin Zhui.
This title was first published in 2003. In laboratories around the world the active principles in traditional herbal medicines are being isolated and characterized. A systematic effort at the Chinese Academy of Sciences is underway to identify the structure-activity relationships that result from the link between chemistry and medicine that is permitted by this data. This book, which provides the only systematic English-language description of the chemical structures and pharmacological effects of compounds active in traditional Chinese medicines (TCMs), is now in its second edition. The new edition provides English-language monographs on over 9000 chemicals isolated from nearly 4000 natural...
From prehistoric bone flutes to Confucian bell-sets, from ancient divination to his beloved qin, this book presents translations of thirteen seminal essays on musical subjects by Jao Tsung-i. In language as elegant and refined as the ancient texts he so admired, his journey takes readers through Buddhist incantation, the philosophy of musical instruments, acoustical numerology, lyric poetry, historical and sociological contexts, manuscript studies, dance choreography, repertoire formulation, and opera texts. His voice is authoritative and intimate, the expert crafting his arguments, both accessible and sophisticated, succinct and richly tapestried; and concealed within a deft modesty is a thinker privileging us with his most profound observation. The musician’s musician, the scholar’s scholar, bold yet cautious, flamboyant yet restrained, a man for all seasons, a harmoniousness of time and place.