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The latest volume in the Advanced Biotechnology series provides an overview of the main product classes and platform chemicals produced by biotechnological processes today, with applications in the food, healthcare and fine chemical industries. Alongside the production of drugs and flavors as well as amino acids, bio-based monomers and polymers and biofuels, basic insights are also given as to the biotechnological processes yielding such products and how large-scale production may be enabled and improved. Of interest to biotechnologists, bio and chemical engineers, as well as those working in the biotechnological, chemical, and food industries.
The submersed cultivation of organisms in sterile containments or fermenters has become the standard manufacturing procedure, and will remain the gold standard for some time to come. This book thus addresses submersed cell culture and fermentation and its importance for the manufacturing industry. It goes beyond expression systems and integrally investigates all those factors relevant for manufacturing using suspension cultures. In so doing, the contributions cover all industrial cultivation methods in a comprehensive and comparative manner, with most of the authors coming from the industry itself. Depending on the maturity of the technology, the chapters address in turn the expression system, basic process design, key factors affecting process economics, plant and bioreactor design, and regulatory aspects.
TWO MONTHS AFTER their disastrous holiday, Orlagh and Jerry are at home in Ireland recovering from their terrifying ordeal. The Belgae Torc is at last on display at the National Museum and Orlagh is under increasing pressure to divide her time between her work at the museum and heading up an archaeological dig in County Meath. She is convinced that an ancient battle between Iron Age tribes took place here and is determined to prove her theory, but as archaeologists begin to unearth the truth, they are faced with some unexpected surprises. Meanwhile, on the other side of the Atlantic, Jack Harrington is making discoveries of his own and finds himself juggling personal and professional commitm...
A collection of upwards of thirty thousand names of German, Swiss, Dutch, French and other immigrants in Pennsylvania from 1727 to 1776: With a Statement of the Names of Ships, Whence They Sailed, and the Date of Their Arrival at Philadelphia.
Green Biocatalysis presents an exciting green technology that uses mild and safe processes with high regioselectivity and enantioselectivity. Bioprocesses are carried out under ambient temperature and atmospheric pressure in aqueous conditions that do not require any protection and deprotection steps to shorten the synthetic process, offering waste prevention and using renewable resources. Drawing on the knowledge of over 70 internationally renowned experts in the field of biotechnology, Green Biocatalysis discusses a variety of case studies with emphases on process R&D and scale-up of enzymatic processes to catalyze different types of reactions. Random and directed evolution under process c...
This issue contains the following articles and [surnames]: Opportunity and Conscience: Mennonite Immigration to Pennsylvania; The Gerber-Vandersaal Cemetery Restoration [Gerber, Vandersaal]; Tempelhof Today [Holly, Ingold]; Update on the Troyer Family [Troyer]; Representing Those Who Moved: Peter Zehr (1874-1960) and Katherine Jantzi (1879-1954) of Ontario, Nebraska, and Oregon, Part III: Peter and Katie Themselves [Zehr, Jantzi]; J. A. Ressler from Lancaster to Scottdale, Pennsylvania [Ressler]; Daniel Shidler (1787-1864), Brethren Farmer in Pennsylvania and Ohio, Part V: The Shidlers' Year in Richland County, Ohio [Shidler, Addleman]; Query on the Schlegel/Slagel Family [Schlegel, Slagel]; Hunting Our Common Zimmermann Ancestor: Combining 21st-Century Genetics With 16th- and 17th-Century Church Records, Part I [Zimmermann, Carpenter]; Query on the Jung/Young Family [Jung, Young]; Colonial Mennonite Immigrants to Eastern Pennsylvania. Browse sample pages here.
In 1727, the Pennsylvania Provincial Council passed a law requiring all "foreign" immigrants (i.e. those of non-British origin) to swear an oath of allegiance to the Crown. Lists of these immigrants were originally assembled for publication in the Pennsylvania Archives (Ser. 2, Vol. XVII), and they are reprinted here without change. This work, then, is an exhaustive list of "foreigners"-mostly Germans-who immigrated into the Province and, later, the State of Pennsylvania between the years 1727 and 1775 and again during the years 1786-1808. More to the point, it is a collection of ships' passenger lists, in many cases the lists being transcribed in entirety, with Captains' lists of passengers running up to the relatively late year of 1808. Along with the full name of the immigrant, including the names of all males over the age of sixteen, since that was the age they were obliged to take the oath, such information is given as name of ship, date of arrival, port of origin, and, in some instances, ages, names of wives, and names of children. An exhaustive index of surnames, running to more than 100 pages, contains about 35,000 references.