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This book brings together the world’s leading authorities on tumor immunology. This book describes the basic immunology principles that form the foundation of understanding how the immune system recognizes and rejects tumor cells. The role of the innate and adaptive immune responses is discussed and the implications of these responses for the design of clinical strategies to combat cancer are illustrated.
A guide to state-of-the-art cancer immunotherapy in translational cancer research A volume in the Translational Oncology series, Immunotherapy in Translational Cancer Research explores the recent developments in the role that immunotherapy plays in the treatment of a wide range of cancers. The editors present key concepts, illustrative examples, and suggest alternative strategies in order to achieve individualized targeted therapy. Comprehensive in scope, Immunotherapy in Translational Cancer Research reviews the relevant history, current state, and the future of burgeoning cancer-fighting therapies. The book also includes critical information on drug development, clinical trials, and govern...
For some time immunotherapy has been heralded as a breakthrough approach for cancer treatment. Although the potential of this strategy remains solid, the approach needs considerable refinement. Whilst some programmes are looking to increase the understanding of molecular and cellular mechanisms underlying the stimulation of antitumor immunity, others are trying to find the most appropriate clinical setting that will reveal the role of the immune system in combating cancer. Among the most important discoveries have been tumor-specific antigens. This thematic volume highlights some key issues and discusses where they may move forward. It has been put together by two leading cancer immunotherapists from two eminent institutions that focus on cancer research.
Molecular Mechanisms That Orchestrate the Assembly of Antigen Receptor Loci, the latest volume in the Advances in Immunology series focuses on the generation of an effective immune response to invading pathogens As B and T lymphocytes are characterized by the expression of antigen receptors that specifically recognize determinants expressed on pathogens, this volume discusses how antigen receptors are synthesized in B and T lymphocytes. - Focuses on the generation of an effective immune response to invading pathogens - Contains contributions from leading authorities - Informs and updates on all the latest developments in the field of immunology
Advances in Immunology, a long-established and highly respected publication, presents current developments as well as comprehensive reviews in immunology. Articles address the wide range of topics that comprise immunology, including molecular and cellular activation mechanisms, phylogeny and molecular evolution, and clinical modalities. Edited and authored by the foremost scientists in the field, each volume provides up-to-date information and directions for the future. - Contributions from leading authorities - Informs and updates on all the latest developments in the field
Advances in Immunology, a long-established and highly respected publication, presents current developments and comprehensive reviews on immunology. Articles address the wide range of topics that comprise immunology, including molecular and cellular activation mechanisms, phylogeny and molecular evolution, and clinical modalities. Edited and authored by the foremost scientists in the field, each volume provides up-to-date information and directions for the future. - Contains contributions from leading authorities - Informs and updates on all the latest developments in the field of immunology
"Authored by some of the world's leading cancer experts from wide ranging disciplines including oncology, radiation oncology, neurosurgery, orthopedic surgery, and radiology this compact volume provides authoritative state-of-the-art primer level overviews of the various cancer types, their evaluation, and treatment. Every aspect of oncology is covered with clear, up-to-date descriptions of the general principles and concepts fundamental to attaining a clinical appreciation of the foundations of cancer care. Each chapter is concise but highlights the basic tenets health care professionals working with cancer patients need to know to understand the diseases and current treatment options. To facilitate review, Key Points are boxed in each chapter to summarize important clinical information and concepts at a glance. This book represents a synthesis of information from some of the top physicians in oncology that is not as easily accessed anywhere else. Features of Synopsis of Clinical Oncology include: Multi-specialty expert authorship Focus on therapeutics management of cancer Key Points boxed in each chapter for quick review "
Advances in Immunology, a long-established and highly respected publication, presents current developments as well as comprehensive reviews in immunology. Articles address the wide range of topics that comprise immunology, including molecular and cellular activation mechanisms, phylogeny and molecular evolution, and clinical modalities. Edited and authored by the foremost scientists in the field, each volume provides up-to-date information and directions for the future. - Contributions from leading authorities - Informs and updates on all the latest developments in the field
Advances in Immunology, a long-established and highly respected publication, presents current developments as well as comprehensive reviews in immunology. Articles address the wide range of topics that comprise immunology, including molecular and cellular activation mechanisms, phylogeny and molecular evolution, and clinical modalities. Edited and authored by the foremost scientists in the field, each volume provides up-to-date information and directions for the future. This volume focuses on tumor immunology. Contributions from leading authorities Informs and updates on all the latest developments in the field
Melanoma is an increasingly important public health problem. Although the cause of most malignant melanomas – over-exposure to ultraviolet light – is well known, effective treatment has remained challenging. The past several years have been marked by extraordinary developments in melanoma treatment in the arena of targeted therapeutics. This book describes these ground-breaking discoveries and their implications for clinical use. As melanoma biology is increasingly understood, so the development of targeted therapies for this disease is spurred ahead. This book covers both established signal transduction inhibitors and the fascinating emerging realm of molecularly-guided immunotherapies. This benchmark book provides the most up-to-date information on the new breed of melanoma therapies. Composed of the works of major researchers and clinicians, this book offers new insights, novel approaches, and promising data for effective treatment planning. Illuminating the latest advances in the field, it is a solid resource for clinical oncologists, translational scientists, and basic cancer researchers.