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Supramolecular host-guest nanosystems for overcoming cancer drug resistance
Cancer drug resistance has become one of the main challenges for the failure of chemotherapy, greatly limiting the selection and use of anticancer drugs and dashing the hopes of cancer patients. The emergence of supramolecular host-guest nanosystems has brought the field of supramolecular chemistry into the nanoworld, providing a potential solution to this challenge. Compared with conventional chemotherapeutic platforms, supramolecular host-guest nanosystems can reverse cancer drug resistance by increasing drug uptake, reducing drug efflux, activating drugs, and inhibiting DNA repair. Herein, we summarize the research progress of supramolecular host-guest nanosystems for overcoming cancer drug resistance and discuss the future research direction in this field. It is hoped that this review will provide more positive references for overcoming cancer drug resistance and promoting the development of supramolecular host-guest nanosystems.
Biology of the Mammary Gland
Proceedings of the European Cooperation in the Field of Scientific and Technical Research (COST 825) Symposium on Mammary Gland Biology, held September 16-18, 1999, in Tours, France. It is difficult to overstate the evolutionary and functional significance of mammary tissue in biology. Substantial progress has been made by researchers in various disciplines, particularly over the last fifteen years, towards realizing the potential of this tissue to yield powerful experimental models for morphogenesis and tissue development; for cellular differentiation; for the biosynthesis and secretion of proteins, lipids, small molecules and inorganic salts; and for the coordination and regulation of thes...
A Companion to Yi jing Numerology and Cosmology
Translations of the Yi jing into western languages have been biased towards the yili ('meaning and pattern') tradition, whereas studies of the xiangshu ('image and number') tradition - which takes as its point of departure the imagery and numerology associated with divination and its hexagrams, trigrams, lines, and related charts and diagrams - has remained relatively unexplored. This major new reference work is organised as a Chinese-English encyclopedia, arranged alphabetically according to the pinyin romanisation, with Chinese characters appended. A character index as well as an English index is included. The entries are of two kinds: technical terms and various other concepts related to the 'image and number' tradition, and bio-bibliographical information on Chinese Yi jing scholars. Each entry in the former category has a brief explanation that includes references to the origins of the term, cross-references, and a reference to an entry giving a more comprehensive treatment of the subject.
Book of Liang, Chen and Wei (Part I) Dynasty
The Twenty-Four Histories (Chinese: 二十四史) are the Chinese official historical books covering a period from 3000 BC to the Ming dynasty in the 17th century. The Han dynasty official Sima Qian established many of the conventions of the genre. Starting with the Tang dynasty, each dynasty established an official office to write the history of its predecessor using official court records. As fixed and edited in the Qing dynasty, the whole set contains 3213 volumes and about 40 million words. It is considered one of the most important sources on Chinese history and culture. The title "Twenty-Four Histories" dates from 1775 which was the 40th year in the reign of the Qianlong Emperor. This ...
Book of Zhou and Sui Dynasty
The Twenty-Four Histories (Chinese: 二十四史) are the Chinese official historical books covering a period from 3000 BC to the Ming dynasty in the 17th century. The Han dynasty official Sima Qian established many of the conventions of the genre. Starting with the Tang dynasty, each dynasty established an official office to write the history of its predecessor using official court records. As fixed and edited in the Qing dynasty, the whole set contains 3213 volumes and about 40 million words. It is considered one of the most important sources on Chinese history and culture. The title "Twenty-Four Histories" dates from 1775 which was the 40th year in the reign of the Qianlong Emperor. This ...
China’s Macroeconomic Outlook
This report is a partial result of China’s Quarterly Macroeconomic Model (CQMM), a project developed and maintained by the Center for Macroeconomic Research (CMR) at Xiamen University. The CMR is one of the Key Research Institutes of Humanities and Social Sciences sponsored by the Ministry of Education of China, focusing on China’s economic growth and macroeconomic policy. The CMR started to develop CQMM for purpose of short-term forecasting, policy analysis, and simulation in 2005. Based on CQMM, the CMR and its partners hold press conferences to release forecasts for China’ major macroeconomic variables. Since July 2006, thirty-three quarterly reports on China’s macroeconomic outlook have been presented.
Dementia and Neurodegenerative Diseases – Case Report Collection 2022
This Research Topic aims to collect all the Case Reports submitted to the Dementia and Neurodegenerative Diseases section. All the Case Reports submitted to this collection will be personally assessed by the Specialty Chief Editor before the beginning of the peer-review process. Please make sure your article adheres to the following guidelines before submitting it. Case Reports highlight unique cases of patients that present with an unexpected diagnosis, treatment outcome, or clinical course. Only Case Reports that are original and significantly advance the field will be considered: - RARE case with TYPICAL features - FREQUENT case with ATYPICAL features - Cases with a convincing response to new treatments, i.e. single case of off-label use
The Alzheimer's Disease Challenge
Alzheimer’s disease is undoubtedly the major health challenge of our Century with significant social and economic consequences. This Frontiers eBook offers a contribution of 39 innovative papers on the multidimensional and crucial problem of Alzheimer’s disease management and treatment. Several perspectives, research updates, and trials describing methods on potential diagnosis and treatment are presented including biological mechanisms, biomarkers and risk factors for an early and efficient prognosis, diagnosis and prevention. Additionally, while the rapidly increasing Alzheimer’s disease population demands holistic solutions and clinical studies with new therapeutic target approaches, several of the contributive papers present promising drugs targeting Alzheimer’s disease treatment. We give our deepest acknowledgment to all the authors for their important and innovative contributions, to the reviewers for their valuable recommendations on improving the submitting studies and all the Frontiers Editorial team for continuous support.
Hydraulic Engineering IV
Hydraulic research is developing beyond traditional civil engineering to satisfy increasing demands in natural hazards, structural safety assessment and environmental research. Hydraulic Engineering IV contains 38 technical papers presented at the 4th International Technical Conference on Hydraulic Engineering (CHE 2016, Hong Kong, 16–17 July 2016), including the 5th International Workshop on Environment and Safety Engineering (WESE 2016) and the 2nd International Structural and Civil Engineering Workshop (SCEW 2016). The sections on hydraulic engineering mainly focus on river engineering and sediment transport, flood hazards and innovative control measures, complex flow modelling, dam saf...
International Conference on Energy and Power Engineering (EPE2014)
The 2014 International Conference on Energy and Power Engineering (EPE2014), will be held on April 26–27, 2014, in Hong Kong, China. The aim of this international convention is to bring together experts and scholars from around the world and offer them a chance to share the latest research results in the field of Energy and Power Engineering. We all know that over the past few decades, a great change has happened in the field of the environment technology, and the science technology is growing faster and faster. In order to keep up with the daily changing situation, we have sent invitations to experts, scholars and other people who have devoted himself in related fields, and it is a great ...
