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Antibiofilm Agents
This book provides a survey of recent advances in the development of antibiofilm agents for clinical and environmental applications. The fact that microbes exist in structured communities called biofilms has slowly become accepted within the medical community. We now know that over 80% of all infectious diseases are biofilm-related; however, significant challenges still lie in our ability to diagnose and treat these extremely recalcitrant infections. Written by experts from around the globe, this book offers a valuable resource for medical professionals seeking to treat biofilm-related disease, academic and industry researchers interested in drug discovery and instructors who teach courses on microbial pathogenesis and medical microbiology.
Antibacterial Drug Discovery to Combat MDR
This book compiles the latest information in the field of antibacterial discovery, especially with regard to the looming threat of multi-drug resistance. The respective chapters highlight the discovery of new antibacterial and anti-infective compounds derived from microbes, plants, and other natural sources. The potential applications of nanotechnology to the fields of antibacterial discovery and drug delivery are also discussed, and one section of the book is dedicated to the use of computational tools and metagenomics in antibiotic drug discovery. Techniques for efficient drug delivery are also covered. The book provides a comprehensive overview of the progress made in both antibacterial discovery and delivery, making it a valuable resource for academic researchers, as well as those working in the pharmaceutical industry.
Making the Medieval Relevant
When scholars discuss the medieval past, the temptation is to become immersed there, to deepen our appreciation of the nuances of the medieval sources through debate about their meaning. But the past informs the present in a myriad of ways and medievalists can, and should, use their research to address the concerns and interests of contemporary society. This volume presents a number of carefully commissioned essays that demonstrate the fertility and originality of recent work in Medieval Studies. Above all, they have been selected for relevance. Most contributors are in the earlier stages of their careers and their approaches clearly reflect how interdisciplinary methodologies applied to Med...
Molecular Medical Microbiology
The molecular age has brought about dramatic changes in medical microbiology, and great leaps in our understanding of the mechanisms of infectious disease. Molecular Medical Microbiology is the first book to synthesise the many new developments in both molecular and clinical research in a single comprehensive resource. This timely and authoritative three-volume work is an invaluable reference source of medical bacteriology. Comprising more than 100 chapters, organized into 17 major sections, the scope of this impressive work is wide-ranging. Written by experts in the field, chapters include cutting-edge information, and clinical overviews for each major bacterial group, in addition to the la...
Kin Recognition in Protists and Other Microbes
Kin Recognition in Protists and Other Microbes is the first volume dedicated entirely to the genetics, evolution and behavior of cells capable of discriminating and recognizing taxa (other species), clones (other cell lines) and kin (as per gradual genetic proximity). It covers the advent of microbial models in the field of kin recognition; the polymorphisms of green-beard genes in social amebas, yeast and soil bacteria; the potential that unicells have to learn phenotypic cues for recognition; the role of clonality and kinship in pathogenicity (dysentery, malaria, sleeping sickness and Chagas); the social and spatial structure of microbes and their biogeography; and the relevance of unicells’ cooperation, sociality and cheating for our understanding of the origins of multicellularity. Offering over 200 figures and diagrams, this work will appeal to a broad audience, including researchers in academia, postdoctoral fellows, graduate students and research undergraduates. Science writers and college educators will also find it informative and practical for teaching.
Medicine in the Talmud
Medicine on the margins -- Trends and methods in the study of Talmudic medicine -- Precursors of Talmudic medicine -- Empiricism and efficacy -- Talmudic medicine in its Sasanian context.
Holy Wells of Ireland
The storied landscapes of Ireland are dotted with holy wells—hallowed springs, pools, ponds, and lakes credited with curative powers and often associated with Catholic and indigenous saints. While many of these sites have been recently lost to development, others are visited daily for devotions and remain the focus of annual community gatherings. Encouraging both their use and protection, Holy Wells of Ireland delves into these irreplaceable resources of spiritual, archaeological, and historical significance. Reserves of localized spiritual practices, holy wells are also ecosystems in themselves and provide habitats for rare and culturally meaningful flora and fauna. The shift toward a "po...
Carolingian Medical Knowledge and Practice, c.775-900
Carolingian Medical Knowledge and Practice explores the practicality and applicability of the medical recipes recorded in early medieval manuscripts. It takes an original, dual approach to these overlooked and understudied texts by not only analysing their practical usability, but by also re-evaluating these writings in the light of osteological evidence. Could those individuals with access to the manuscripts have used them in the context of therapy? And would they have wanted to do so? In asking these questions, this book unpacks longstanding assumptions about the intended purposes of medical texts, offering a new perspective on the relationship between medical knowledge and practice.
A Natural History of the Future
"An arresting vision of this relentless natural world"—New York Times Book Review A leading ecologist argues that if humankind is to survive on a fragile planet, we must understand and obey its iron laws Our species has amassed unprecedented knowledge of nature, which we have tried to use to seize control of life and bend the planet to our will. In A Natural History of the Future, biologist Rob Dunn argues that such efforts are futile. We may see ourselves as life’s overlords, but we are instead at its mercy. In the evolution of antibiotic resistance, the power of natural selection to create biodiversity, and even the surprising life of the London Underground, Dunn finds laws of life that no human activity can annul. When we create artificial islands of crops, dump toxic waste, or build communities, we provide new materials for old laws to shape. Life’s future flourishing is not in question. Ours is. As ambitious as Edward Wilson’s Sociobiology and as timely as Elizabeth Kolbert’s The Sixth Extinction, A Natural History of the Future sets a new standard for understanding the diversity and destiny of life itself.
Cultures of Healing
This volume brings together for the first time an updated collection of articles exploring poverty, poor relief, illness, and health care as they intersected in Western Europe, the Mediterranean and the Middle East, during a ‘long’ Middle Ages. It offers a thorough and wide-ranging investigation into the institution of the hospital and the development of medicine and charity, with focuses on the history of music therapy and the history of ideas and perceptions fundamental to psychoanalysis. The collection is both sequel and complement to Horden’s earlier volume of collected studies, Hospitals and Healing from Antiquity to the Later Middle Ages (2008). It will be welcomed by all those interested in the premodern history of healing and welfare for its breadth of scope and scholarly depth.
