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The purpose of this textbook is to meticulously depict all aspects of chest tumors in a comprehensive volume format that encompasses their biology, clinical presentation and management. It is the only book to do this. Chapters of specific interest have also been included to cover such wide-ranging topics as management of the elderly and chemoprevention, along with ethical, social and financial issues associated with such tumors. All participating authors, selected from an international panel of highly regarded scientists currently pioneering lung cancer research, are major contributors in the area of expertise they have been chosen to present.
A truly comprehensive reference for the management of patientswith endocrine cancer The new edition of Clinical Endocrine Oncology has beenfully revised and extended making it the most comprehensive andup-to-date reference available. Written and edited by leadinginternational experts in the field, it sets the standard inmultidisciplinary care for patients with endocrine tumors. The book provides specific and detailed guidance on the basic,clinical, investigative and therapeutic processes required for thethorough evaluation of a patient with a tumor in an endocrineorgan. The eighty-four chapters are arranged in seven parts: • Endocrine Oncology and Therapeutic Options • Thyroid and Parath...
Gene therapy as a treatment for cancer is at a critical point in its evolution. Exciting new developments in gene targeting and vector technology, coupled with results from the first generation of preclinical and clinical studies have led to the design and testing of new therapeutic approaches. The Third Edition of Gene Therapy of Cancer provides crucial updates on the basic and applied sciences of gene therapy. It offers a comprehensive assessment of the field including the areas of suicide gene therapy, oncogene and suppressor gene targeting, immunotherapy, drug resistance gene therapy, and the genetic modification of stem cells. Researchers at all levels of development, from basic laborat...
This is an open access book. With a wealth of exciting data emerging in this rapidly evolving field this book will review the state-of-the-art knowledge with emphasis on multidisciplinary decision and management of head and neck cancer. The book provides significant detail on a wide range of topics including: the role of new targets for treatment, immunotherapy, resistance mechanisms, standardizing molecular profiling programs, and new methods to guide therapeutic approaches. In addition different disease situations are addressed including different treatment approaches in primary disease and in recurrent and/or metastatic disease as well as new developments in pathology, surgery and reconstruction techniques, new systemic therapies in salivary gland cancer, and supportive care and follow-up. All disciplines involved in the treatment of head & neck cancer are covered with a focus on translation into daily practice. The 8th-THNO is designed for medical oncologists, head and neck surgeons, radiation oncologists, otolaryngologists, and other medical professionals involved in the treatment of patients with head and neck cancer.
In the last decade there has been an explosion of interest in viral therapies for cancer. Viral agents have been developed that are harmless to normal tissues but selectively able to kill cancer cells. These agents have been endowed with additional selectivity and potency through genetic manipulation. Increasingly these viruses are undergoing evaluation in clinical trials, both as single agents and in combination with standard chemotherapy and radiotherapy. This book provides a comprehensive yet succinct overview of the current status of viral therapy of cancer. Chapters coherently present the advances made with individual agents and review the biological and clinical background to a range o...
Post-laryngectomy rehabilitation has generated tremendous interest in recent times owing to the development of innovative prosthetic devices and other appliances aimed at making life more comfortable for the laryngectomee. This book addresses not only the very essential function of voice rehabilitation, but also other equally important aspects such as pulmonary, olfactory and psycho-social rehabilitation as well as quality-of-life issues after laryngectomy. With more and more ENT, head and neck surgeons performing laryngectomies on a regular basis, this book aims to provide both the trainees and practicing surgeons a comprehensive and practical guide to the total rehabilitation of these patients.
This book presents a detailed overview of the development of new viral vector-based vaccines before discussing two major applications: preventive vaccines for infectious diseases and therapeutic cancer vaccines. Viral vector-based vaccines hold a great potential for development into successful pharmaceutical products and several examples at the advanced pre-clinical or clinical stage are presented. Nevertheless, the most efforts were focused on novel and very innovative technologies for new generation of vector-based vaccines. Furthermore, specific topics such as delivery and adjuvant and protection strategies for cell-mediated-based vaccines are presented. Given its scope, the book is a “must read” for all those involved in vaccine development, both in academia and industrial vaccine development.
In this issue of Oral and Maxillofacial Surgery Clinics, guest editor Dr. Al Haitham Al Shetawi brings his considerable expertise to the topic of Management of Melanoma in the Head and Neck. Top experts in the field cover key topics such as reconstruction of melanoma defects, management of mucosal melanoma, adjuvant therapies in melanoma, future treatments in melanoma, and more. - Contains 10 relevant, practice-oriented topics including classification and staging of melanoma, management of the regional lymph nodes, imaging and laboratory work-up for melanoma, principles of melanoma surgery, and more. - Provides in-depth clinical reviews on melanoma management in the head and neck, offering actionable insights for clinical practice. - Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.