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This book reflects the state of the art of our understanding of the WNT signaling system, which comprises a network of signaling pathways initiated by the secreted WNT lipoglycoproteins, which are crucial for embryonal development, stem cell regulation, tissue homeostasis and repair. Dysfunction of this evolutionarily conserved signaling system leads to many diseases including developmental disorders, diverse forms of cancer, fibrosis, neurodegenerative disease and many more. The WNT signaling system is built upon 19 mammalian, secreted WNT lipoglycoproteins that interact with a plethora of distinct receptors, such as the G protein-coupled receptors called Frizzleds (FZD1-10), LDL receptor-l...
Ferrites are highly interesting high-tech materials. The book covers their classification, structure, synthesis, properties and applications. Emphasis is placed on biomedical applications, degradation of organic pollutants, high frequency applications, photocatalytic applications for wastewater remediation, solar cell applications, removal of organic dyes and drugs from aquatic systems, and the synthesis of hexagonal ferrites. Keywords: Ferrite, Spinel Ferrite Nanoparticles, Biomedical Applications, Ferrite Based Heterojunction, Photocatalytic Degradation of Organic Pollutants, Nickel-Zinc Ferrites, Spinel Ferrite Based Nanomaterials, Water Remediation, Magnetic Nano Particles, Wastewater Treatment, Piezo-Phototronic Effect, Ferrite Based Solar Cells, Aurivillius Based Ceramics, Hexagonal Ferrites.
The book covers the entire spectrum of magnetic nanomaterials and their highly interesting properties. It also discusses engineering strategies and current applications of magnetic nanomaterials in analytical chemistry, spintronics, biomedical science, electrochemistry, energy storage and conversion, membranes and fuel cells. Keywords: Magnetic Nanomaterials, Analytical Chemistry, Biomedical Science, Spintronics, Electrochemistry, Energy Storage, Energy Conversion, Membranes, Fuel Cells, Bio-Sensors, Electrocatalysis, Separation Processes, Hydrogen Storage, Supercapacitors, SERS Effect.
Polymeric Nanoparticles as Promising Tool for Anti-cancer Therapeutics provides an understanding of polymeric compounds and their use in cancer therapies. The book begins by giving an overview of the current status, future challenges and potential utilization of polymeric nanoparticles. It then covers specific polymeric nanoparticles through contributions from world-renowned experts and researchers. Chapters examine specific polymeric nanoparticles, their development as potential targeted delivery systems, and cancer characteristics that can be targeted for therapy development. The book synthesizes current research trends in the field, thus enhancing existing knowledge of nanomedicine, drug ...
Oncogenic Viruses: Medical Applications of Viral Oncology Research, Volume Two builds on the introductory overview of Volume One, Oncogenic Viruses: Fundamentals of Oncogenic Viruses. It looks at recent advances and medical application of research studies on oncoviruses, including examining oncoviruses on a molecular level, covers diagnostic and prognostic viral biomarkers and identifying biomarkers in specific human cancers, and delves into prevention, treatment and the future of cancer therapy of oncoviruses, antiviral activities and vaccination strategies. Advanced topics and the future direction of oncovirology round out the book. This book is a comprehensive reference for researchers and practitioners engaged in learning more about the role of oncogenic viruses in the pathogenesis of human cancers and how that information can be applied to identify strategies for prevention and treatment. - Explores the biology of oncoviruses and mechanisms of action on a cellular level - Examines recent advances in oncoviruses prevention and curative treatments - Discusses the use of modeling and bioinformatics in research studies on oncoviruses
Nanomedicine in Cancer Immunotherapy bridges the two disciplines of nanotechnology and immunology, summarizing the latest research into novel cancer treatments, often personalized to the patient.This book covers a wide range of nanomaterial types for use in cancer immunotherapy, including hydrogel, lipid, exosome, gold and peptide nanoparticles. The preparation, application, pros and cons of each nanomaterial class is reviewed, helping the reader understand the potential for each and tailor their selection to their needs. Nanovaccines are also covered, along with a clinical evaluation and market analysis of nanomedicines for immunotherapy, offering an important clinical and commercial overvi...
Functionalized Nanoclays: Synthesis and Design for Industrial Applications presents a thorough and in-depth overview of functionalized nanoclays, from an introductory presentation of different nanoclays and their characterization, to their properties, synthesis, fabrication methods and applications in various industries. This book begins with an introduction to functionalized nanoclays and their composites, followed by sections dedicated to theoretical aspects and material synthesis. Subsequent chapters cover a broad range of industrial applications including pollution remediation, sensing, drug delivery, food packaging, and much more. The following section discusses recent progress in comme...
This volume of Pharmaceutical Biocatalysis starts with a discussion on the importance of biocatalytic synthesis approaches for a sustainable and environmentally friendly production of pharmaceuticals and active pharmaceutical ingredients. Among the enzymes discussed in detail with respect to their pharmaceutical relevance are cyclic nucleotide phosphodiesterases playing an important role in modulating signal transduction in various cell types; human DOPA decarboxylase, related to Parkinson's disease and aromatic amino acid decarboxylase deficiency; and phospholipase D enzymes as drug targets. Isocitrate dehydrogenase 1 and 2 mutations are novel therapeutic targets in acute myeloid leukemia. ...
Publications in nanoscience cross conventional boundaries from chemistry to specialised areas of physics and nanomedicine. With such a vast landscape of material, careful distillation of the most important discoveries helps researchers find the key information. This volume provides a critical and comprehensive assessment of the most recent research and opinion from across the globe. Topics covered include single atom catalysts for water splitting, bacteriophages for nanotechnology, preparation of nanomaterials for scanning electrochemical techniques, noise spectroscopy of nanomaterials, and sustainable energy harvesting. Appealing to anyone practising in nano-allied fields or wishing to enter the nano-world, this useful resource provides a succinct reference on recent developments in this area now and looking to the future.
As Ellen Bercheid points out in her foreword to this volume, relationship science is a complex and ever expanding field. Much credit goes to editors Clyde Hendrick and Susan S. Hendrick for their scholarly dedication to the advancement of this multidisciplinary arena. This sourcebook demonstrates, yet again, their expertise and leadership as they succeed in combining many great contributions to the field by some of the most respected specialists around. Read this book for a panoramic view of close relationship research with highlights from current literature, original research, practical applications, and projections for future research.