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Spirochetes and Immune Evasion: Infection, Persistence and Clearance
The interface between spirochetes and the immune response is of significant importance to their pathogenesis and persistence. Evasion from the immune system leads to infections that present as Leptospirosis, Syphilis, Lyme Disease and Relapsing Fever and may lead to putative persistence and latency. Understanding the mechanisms involved in immune evasion will shed light not only on the hostpathogen factors involved in the process but also on how resistance to infection leads to protection. Broad examples include spirochetal interaction with the immune system, spirochetal molecules involved in immune evasion and in immune activation, innate immune responses in the skin and other compartments,...
Global excellence in infectious diseases – Surveillance, prevention and treatment: Central and South America
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Molecular Vaccines
This book gives a comprehensive overview to all aspects of global molecular vaccine research. It introduces concepts of vaccine immunology and molecular vaccine development for viral, bacterial, parasitic and fungal infections. Furthermore, the broad field of research and development in molecular cancer vaccines is discussed in detail. This book is a must have for scientists and clinicians interested in new developments in molecular vaccine research and application in infections and cancer.
Lyme Disease: Recent Advances and Perspectives
The interplay between host and pathogen is a complex co-evolutionary battle of surveillance and evasion. The pathogen continuously develops mechanisms to subvert the immune response in order to establish infection while the immune system responds with novel mechanisms of detection. Because the majority of Lyme disease pathology is due to an over-exuberant immune response, much research in Borrelia burgdorferi pathogenesis has been devoted to understanding the mammalian host response to the bacterium. Immunological studies continue to be an active area of research employing emerging techniques, such as intra-vital imaging. These studies have furthered our understanding of inflammatory process...
The Immunological Consequences of Regulated Cell Death in Infection and Inflammation
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Pathogenesis of Leptospira
The present eBook, consisting of a compilation of research and review articles, focuses on the features and mechanisms adopted and explored by pathogenic leptospires to successfully establish infection in the host. Additionally, this eBook provides information to support future work focused on the development of new prevention approaches against this important yet neglected zoonotic disease.
Environmental Health in the 21st Century [2 volumes]
This concisely written and easy-to-read resource provides information on emerging issues and valuable historical context that enables students to better understand a broad range of environmental health topics, from pollution to infectious diseases, natural disasters, and waste management. As technology enables better insight into the world we live in, we are increasingly aware of environmental health concerns and risks, from contaminated air and water to infectious diseases and light and noise pollution. Because the quality of our lives depends on the quality of our environment, everyone should be informed about issues in environmental health. Environmental Health in the 21st Century: From A...
