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Diagnostic Approaches for Aspergillus Infections
Infections caused by Aspergillus spp. are associated with devastating mortality rates. Early and reliable diagnosis and subsequent rapid initiation of appropriate antifungal therapy has shown to improve survival significantly, at least for invasive Aspergillosis. Early diagnosis of Aspergillus associated infections, therefore, represents a cornerstone in successful management of these diseases. Current state of the art diagnostic approaches, new insights in epidemiology and established biomarkers as well as an outlook for future diagnostic options in the armamentarium of diagnostics tools are highlighted in this eBook.
Infection Management in Hematology
This book provides a thorough update on the management of infections in patients with hematologic malignancies, focusing particularly on prevention, diagnosis, and treatment. Detailed attention is devoted to the central roles that vaccination and anti-infective prophylaxis have gained in improving overall survival in this patient group, in accordance with the principle that prevention is better than cure. Careful consideration is also paid to risk stratification, which is crucial in ensuring that anti-infective prophylaxis is targeted to those at the highest risk. While preventive strategies reduce the prevalence of infections, optimized management strategies are vital to decrease infection-related morbidity and mortality in those who nevertheless develop infections. Here, readers will find in-depth, up-to-date knowledge on the diagnosis and treatment of bacterial, fungal, viral, and parasitic infections, according to the affected organ and the causative pathogen. Finally, treatment in intensive care units is reviewed. The book will be of high value for hematologists, oncologists, and infection specialists.
Infection Management in Hematology
This book provides a thorough update on the management of infections in patients with hematologic malignancies, focusing particularly on prevention, diagnosis, and treatment. Detailed attention is devoted to the central roles that vaccination and anti-infective prophylaxis have gained in improving overall survival in this patient group, in accordance with the principle that prevention is better than cure. Careful consideration is also paid to risk stratification, which is crucial in ensuring that anti-infective prophylaxis is targeted to those at the highest risk. While preventive strategies reduce the prevalence of infections, optimized management strategies are vital to decrease infection-related morbidity and mortality in those who nevertheless develop infections. Here, readers will find in-depth, up-to-date knowledge on the diagnosis and treatment of bacterial, fungal, viral, and parasitic infections, according to the affected organ and the causative pathogen. Finally, treatment in intensive care units is reviewed. The book will be of high value for hematologists, oncologists, and infection specialists.
COVID-19 Viral Sepsis
COVID-19 Viral Sepsis: Impact on Disparities, Disability, and Health Outcomes introduces the concepts of viral sepsis, its origins, and its implications. COVID-19 is a leading cause of viral sepsis with considerable impact on morbidity and mortality. Early recognition of signs and symptoms of COVID-19 can potentially impact patient outcomes. The book opens with an introduction and overview of sepsis, its clinical manifestations, prevention, and management. It goes on to discuss viral sepsis and sepsis caused by COVID-19. COVID-19, its diagnosis, management, sequelae, long-term consequences, challenges, and opportunities round out the coverage. Users will find valuable key principles related to the recognition, prevention, diagnosis and treatment of sepsis due to COVID-19. - Provides an overview of the clinical picture of COVID-19 associated viral sepsis. - Examines structural racism, COVID-19 related healthcare disparities, and the impact of this infectious disease on various communities. - Discusses challenges of secondary bacterial and fungal infections and long-term consequences of COVID-19 as well as opportunities for treatment.
Host and Pathogen Determinants of Allergic and Invasive Fungal Diseases
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Fungal Infections Complicating COVID-19
Coronavirus disease 2019 (COVID-19), caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), spread globally to pandemic proportions. Although the majority of cases have asymptomatic or mild infections, a significant proportion of cases progress to severe pneumonia and acute respiratory distress syndrome requiring critical care. Opportunistic infections following severe respiratory viral infections have been recognized since the 1918 influenza pandemic. Among critically ill patients with COVID-19, secondary fungal infections caused by Aspergillus and Candida spp. are increasingly described, affecting up to 30% of COVID-19 patients requiring intensive care treatment. This collection of manuscripts focuses on fungal infections complicating COVID-19, including immunological mechanisms and pathogenesis, diagnosis, and treatment.
Antimicrobial Immune Response
Infectious microbial agents such as viruses, bacteria, fungi, and parasites can cause pathological disorders and even death in organisms exposed to the environment. However, organisms have an immune system to control infection caused by pathogens. The immune system is divided into the innate and the adaptive immune systems. The innate immune system is the first mechanism to respond to infections, whereas the adaptive immune system is based on immune memory. This book provides an overview of antiviral and antibacterial immune responses in different immune-reactive organs and across different animal species, from higher to lower vertebrates.
States of Health
States of Health identifies the practical relevance of federalism in the United States to people facing ethical decisions about health and health care, and it considers the theoretical justifications for permissible differences among states. It asks whether authority over important aspects of health is misaligned in the United States today, with some matters problematically left to the states while others are taken over by the federal government.
