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Genetic Disease Discovery and Therapeutics
Genetic Disease Discovery and Therapeutics presents information on the methods used to determine how specific gene defects influence pathology and phenotype and to review novel therapeutic approaches designed for the treatment of specific genetic and genomic disorders.This book investigates methodologies applied to the characterization of downstream functional effects of specific gene mutations associated with altered phenotypes and clinical disease. It documents evidence of how specific mutations influence pathology and lead to disease manifestations. This book also reviews information on therapeutic approaches that could potentially be applied in diseases due to gene defects. Genetic Disea...
Tuberous Sclerosis Complex
Tuberous Sclerosis is a genetic disease characterized by lesions of the skin and central nervous system, seizures, and sometimes sever mental retardation. Infants with this disease may appear overactive, autistic, or socially impaired. Because tuberous sclerosis involves abnormal cellular differentiation, aberrant neuronal migration, and excessive cell proliferation, this thoroughly revised edition will be of interest to a wide range of professionals involved in the study of biological mechanisms underlying many genetically determined neurological disorders.
Advances in Human Genetics
Continues the annual series presenting review articles designed to keep specialists abreast of advances in other disciplines working on human genetics. The five reviews cover genital adrenal hyperplasia, amyloidosis, Huntington's disease, cystic fibrosis, and von Recklinghausen neurofibromatosis. An
Nitrogen Fixation with Non-Legumes
Biological fixation of nitrogen by organisms and associations other than those concerned in the legume-Rhizobium symbiosis has attracted increasing attention since the firstintemationalworkshop on the theme at Piracicaba, Brasil, in 1979. Approximately 150 scientists gathered on September 2-8, 1984, at the Hanasaari Cultural Centre near Helsinki, Finland, for the third international meeting on nitrogen fixation with non-legumes. Forty-two papers and 39 posters were presented; 32 of the papers have been broughttogetherin this publication. The Symposium was generously sponsored by the FinnishNational Fund for Research and Development (SITRA) in connection with a large project on biological nit...
The Effects of Maternal Alcohol and Drug Abuse on the Newborn
Drug abuse and alcoholism specialists present the latest findings on the effects on the newborn of mothers' use of illicit drugs during pregnancy. These experts specifically address the perinatal, neonatal, and subsequent developmental effects.
