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There are 7,000 rare diseases affecting 6%–8% of the global population. That's 3.5 million people in the UK alone. Yet only 200 rare diseases have approved treatments. In recent years, there has been a surge of interest from business and social entrepreneurs in the field of health – including looking at ways to treat rare disease patients better and faster. This book presents some of the latest developments in the world of rare disease entrepreneurship from a global group of experts. It examines the topic from the business angle, considering the drug development process and providing case studies of successful orphan drug enterprises. It also looks at rare diseases from the perspective o...
It is increasingly clear that fifty years of international development have done little to reduce poverty in Africa. Indeed, more and more academics and practitioners are highlighting the detrimental effect of traditional development – as carried out by international agencies and NGOs – which often leads to dependency, inefficiency, waste and poor governance. Yet there is a new movement that is surging ahead in its attempt to reduce poverty and generate wealth in Africa: microfranchising. Set up by pioneering organizations such as VisionSpring and HealthStore, microfranchising is based on one of the most successful market-based models in Western economies: franchising. From McDonald's to...
An analysis of the production and consumption of the communications of Make Poverty History , a high profile episode of social movement protest in the UK. The book follows the campaign throughout its lifetime and explores how attitudes towards government and political opportunities influenced the negotiation of communications.
They say you should walk towards the light. Well I didn't. I fled. I ran away from it. I pushed the light back and it splintered in my hands like glass. I thought I might be dead because there was no blood. I raged, I wept. I shouted. There was no pain. I screamed. There was no noise. It wasn't time. It wasn't right. But still, I did not know that I was dead. Still, I hoped that I was not. I wasn't ready... Has it been done before? We don't think so. Dual authorship is one thing, but fifteen authors? That's more like a writing team for a soap opera or a big TV series than a single novel. And who are the Dark Angels? Well, they're not bikers or Goths or heavy metal rockers, but an eclectic bu...
If you read only one book on business writing, make it this one. Chapters by the twelve partners of the Dark Angels Collective set out a comprehensive approach to writing more effectively for business. For nearly twenty years the Dark Angels programme has been championing the cause of more human, more emotive writing in the business world – because it’s this kind of writing that works, in branding, in copywriting, in writing for design, in annual reports, in all genres and all sectors. The Dark Angels approach is to draw on techniques from fiction, poetry and memoir to tell better stories – stories that connect with readers across all commercial media. The results, endorsed here by many of the most respected writers in the field, are gathered in this book as an indispensable source of inspiration and practical advice. It’s the book that sets the new benchmark for professional writers.
Drug repurposing, or repositioning, is the development of existing drugs for new uses: given that 9 in 10 drugs that enter drug development are never marketed and therefore represent wasted effort, it is an attractive as well as inherently more efficient process. Three repurposed drugs can be brought to market for the same cost as one new chemical entity; and they can also be identified more quickly, an important benefit for patients whose diseases are progressing faster than therapeutic innovation. But repurposing also requires a fresh look at configuring pharmaceutical R&D, considering clinical, regulatory and patent issues much earlier than would otherwise be the case. In addition to new ways of thinking, the discovery of repurposing opportunities can take advantage of artificial intelligence techniques to match the perfect new use for an existing drug. This book provides an ideal introduction to the field of drug repurposing with contributions from world-renowned experts culminating in an excellent resource for any drug discovery or medicinal chemist.
The story of Alpha is of major significance for understanding the place of religious faith in the modern world, but that story has never been told - until now. Since its launch in 1993, the Alpha movement has evolved from 'supper party evangelism' in the Kensington suburbs into a global brand of Christian outreach. Today, over a million people attend Alpha every year, but the history of its rise to popularity has never been documented. What caused such spiritual renewal in an age of scepticism? And what propelled Alpha into a phenomenon that is recognised across the globe? Alpha is far more than an introductory course to Christianity. At the core of its brand identity is a 'repackaging' of t...
What are ‘global crises' and how do they differ from earlier crises? What do recent studies of global crises reporting tell us about the role of the news media in the global age? What are the current trends in the fields of journalism and civil society that are now re-shaping the public communication of crises? From climate change to the global war on terror, from forced migration to humanitarian disasters - these are just some of the global crises addressed in this accessible, ground-breaking book. For the first time, the author situates diverse threats to humanity in a global context and examines how, why and to what extent they are conveyed in today's news media. Global crises are conce...
Many social entrepreneurs struggle to take successful, innovative programs that address social problems on a local or limited basis and scale them up to expand their impact in a more widespread, deeper, and efficient way. In Scaling Social Impact , the editors address this issue with a comprehensive collection of original papers.
In Moral Pressure for Responsible Globalization, Sherrie M. Steiner offers an account of religious diplomacy with the G8, G7 and G20 to evoke new possibilities in an effort to influence globalization to become more equitable and sustainable. Commonly portrayed as ‘out of control’, globalization is considered here as a political process that can be redirected to avoid the tragedy of the global commons. The secularization tradition of religion depicts faith-based public engagement as dangerous. Making use of historical materials from faith-based G-plus System shadow summits (2005-2017), Steiner provides ample information to arrive at an interpretation that significantly differs from traditional accounts. Using broader scope conditions, Steiner considers how human induced environmental changes contribute to religious resurgence under conditions of weakening nation states.