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Dealing with all the aspects of diabetes in clinical practice, this book offers a comprehensive, easy-to-use guide to help healthcare professionals achieve their target of optimal management and treatment of their patients. Diabetes in Clinical Practice: Questions and Answers from Case Studies is presented in the form of questions concerning diabetes diagnosis, management and therapy based on real-life case studies. Each question is answered in a clear, easy to follow style. The authors begin with general questions regarding diabetes, its pathophysiology and diagnostic tests. They then cover all the major complications that can arise in a patient with poorly controlled diabetes. The authors ...
Foot ulcers occur in approximately 15% of the patients with diabetes mellitus in their lifetime, with a major impact on their quality of life. Many hospital admissions related to diabetes are due to foot ulcers, which can result in prolonged hospital stay and increased morbidity and mortality. The majority of lower limb amputations are performed in patients with diabetes every year (80,000 at least in the USA). Most of the diabetes-related foot problems can be prevented or their severity reduced by early detection and treatment. This book contributes to improved foot care through raised awareness of prevention, clinical manifestations, diagnosis and management among healthcare professionals....
In the fourth edition of this gold-standard title, a distinguished panel of experts provides a thorough update of the significant improvements in our understanding of diabetic foot physiology and its clinical management. Divided into three sections, the first part focuses on clinical features and diagnosis; the second on pathophysiology; and the third on the management of diabetic foot problems. In addition to updating all previous chapters, several new contributions have been added, reflecting advances in our understanding of the causes of diabetic foot ulcers and efforts to develop new and more effective therapies. The authors, many practicing at the famous Joslin-Beth Israel Deaconess Foo...
Many foot problems in diabetes can be prevented and often the patients are misdiagnosed, or inappropriately referred or treated. This title will be of immense use to the audience as work of reference. Diabetes mellitus is the lack of insulin leading to uncontrolled carbohydrate metabolism, the breakdown of starches and sugars into smaller units that can be used by the body for energy. Foot ulcers occur in about 15% of diabetic patients in their lifetime and hospital admissions due to foot ulcers are very common. Foot problems mostly occur when there is nerve damage in the feet or when there is poor blood flow. * Contains colour photos and pictures * Examples for identification of the patients at risk for foot ulceration * Prompt diagnosis and treatment.
The book explores both the clinical presentation of serious diabetic emergencies (like ketoacidosis, hyperosmolar coma, and severe hyper and hypoglycemia) that consultants and hospital staff encounter in practice and the best methods of both managing the emergencies and also administering follow-up guidance/care. All chapters are clearly structured to highlight: definition of emergency; epidemiology; potential causes, diagnosis, clinical management (including problem areas), follow-up management/care; and patient advice. There are case studies to aid clinical understanding, as well as 5-7 multiple choice questions and several key points/take-home message boxes in every chapter.
The revised and updated third edition of the essential guide to the diagnosis and treatment of the diabetic foot The revised third edition of the Atlas of the Diabetic Foot is an updated guide to the information needed for the prevention and treatment of diabetic foot problems with the aim of reducing amputations. In addition to offering the theoretical knowledge, the book is filled with more than 500 color photos from real-life cases. The cases explore a wide-variety of foot issues and the text includes information about differential diagnosis and treatment. The authors—noted experts in the field—describe the epidemiology, pathophysiology and classification of diabetic foot ulcers. In a...
This comprehensive book addresses all elements of the autonomic nervous system (ANS) and sleep interaction, as well as ANS alterations in sleep and how these impact primary and comorbid sleep dysfunction. It meets the market need for a comprehensive text that deals with ANS changes in sleep and how these impact various neurological, medical, and primary sleep disorders. Organized into three parts, the book begins with a review of the foundational bodily systems that participate in coordination of ANS activity with other homeostatic responses such as respiration, cardiovascular reflexes, and responses to stress. Part two then examines methods of laboratory evaluation and the “why, when, how” of interpreting heart rate variability in sleep. To conclude, the final section of the book broadly covers the many clinical aspects of ANS, including insomnia, restless leg syndrome, sleep apnea, sleep related epilepsy, and acute autonomic neuropathy. Autonomic Nervous System and Sleep enhances the reader's understanding of the pathophysiology of various disorders, and explains how to apply this profound understanding is important to new lines of therapy to improve morbidity.
The impact of information technology on the management of healthcare has been enormous in recent years, and it continues to grow in scope and complexity. This book presents papers from the 2014 International Conference on Informatics, Management, and Technology in Healthcare (ICIMTH), held in Athens, Greece, in July 2014. The book includes 79 full papers and 12 poster presentations as well as keynotes, two workshops and three tutorials. Papers are divided into sections including: clinical informatics; decision support and intelligent systems; e-learning and education; health informatics, information management and technology assessment; healthcare IT; mobile technology in healthcare; public health informatics and issues; social and legal issues; and telemedicine. The book will be of interest to all those whose work involves the use of biomedical and health informatics.
Type 2 diabetes (T2D) is a complex metabolic disorder characterized by impaired glucose metabolism and pancreatic β-cell dysfunction. No effective treatments are available for T2D, although there have been many developments in the therapeutic arena. Nitric oxide (NO) is an endocrine agent with multiple and important biological roles in most mammalian tissues. NO has emerged as a central regulator of energy metabolism and body composition. NO bioavailability is decreased in T2D. Several of the pharmaceuticals used in T2D affect the NO system and perhaps even more so by the drugs we use to treat diabetic cardiovascular complications. Experimental works in animal models of T2D show promising r...
This book explores the intricate world of plant signaling by unraveling the synergistic roles of salicylic acid and nitric oxide in plant adaptation. This captivating exploration illuminates the pivotal roles of salicylic acid (SA) and nitric oxide (NO) as master regulators of plant responses to changing environmental dynamics. SA, a phenolic maestro, wields its mastery in steering metabolic pathways, stimulating plants’ tolerance against abiotic stresses. Meanwhile, the enigmatic nitrogen monoxide (NO) emerges as a redox regulator, modulating growth and physiology amid high temperature stress. NO's role as a second messenger resonates through physiological processes, igniting antioxidant defenses, modulating osmolyte levels, and harmonizing stress-responsive genes. This volume seeks to highlight the covert alliance between SA and NO, more specifically their potential collaboration in alleviating high temperature-induced oxidative stress. The book offers basic yet enchanting voyage into the nexus of plant adaptation.