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Proteomic Profiling and Analytical Chemistry: The Crossroads, Second Edition helps scientists without a strong background in analytical chemistry to understand principles of the multistep proteomic experiment necessary for its successful completion. It also helps researchers who do have an analytical chemistry background to break into the proteomics field. Highlighting points of junction between proteomics and analytical chemistry, this resource links experimental design with analytical measurements, data analysis, and quality control. This targeted point of view will help both biologists and chemists to better understand all components of a complex proteomic study. The book provides detaile...
All aspects of the relationship between the elaboration of exoenzymes and the virulence of bacteria are addressed in the following pages. The authors have provided the most current information available in their areas of expertise. In circumstances where definitive information is lacking, the speculations of the authors should prove interesting to the reader.
This book contains examples written by internationally recognized experts applying proteomics and analysis applications of mass spectrometry in their everyday research. They dedicate this book to a broad audience of all scientists to encourage them to use the omics approach to investigate biological processes.The first chapter is a short introduction to the basics of analytical chemistry. The following chapters describe high-throughput proteomic studies and how they are applied in various areas of biological and biomedical sciences, providing valuable insights into how biological systems work at the molecular level.
From basic science to clinical care, to epidemiological disease patters, The Neurology of AIDS is the only complete textbook available on AIDS neurology and the only one comprehensive enough to stand alone in each segment of study in brain disorders affected by the human immunodeficiency virus. It is an indispensable resource for students, resident physicians, practicing physicians, and for researchers and experts in the HIV/AIDS field. Oxford Clinical Neuroscience is a comprehensive, cross-searchable collection of resources offering quick and easy access to eleven of Oxford University Press's prestigious neuroscience texts. Joining Oxford Medicine Online these resources offer students, specialists and clinical researchers the best quality content in an easy-to-access format.
The mucins (mucus glycoproteins) have long been a complex corner of glycoprotein biology. While dramatic advances in the separation, structural an- ysis, biosynthesis, and degradation have marked the progress in general glycop- tein understanding, the mucins have lagged behind. The reasons for this lack of progress have always been clear and are only now being resolved. The mucins are very large molecules; they are difficult to separate from other molecules present in mucosal secretions or membranes; they are often degraded owing to natural protective functions or to isolation methodology and their peptide and oligos- charide structures are varied and complex. Understanding these molecules h...
A Companion to Medical Anthropology examines the current issues, controversies, and state of the field in medical anthropology today. Provides an expert view of the major topics and themes to concern the discipline since its founding in the 1960s Written by leading international scholars in medical anthropology Covers environmental health, global health, biotechnology, syndemics, nutrition, substance abuse, infectious disease, and sexuality and reproductive health, and other topics
A comprehensive state-of-the-art summary of breast cancer research and treatment by leading authorities. The book's many distinguished contributors illuminate the biology and genetics of breast cancer, including what is known about the hereditary breast cancer genes, BRCA1 and 2, the cutting-edge cytogenic approaches, and the biology of breast cancer metastasis. In addition, the authors describe current and future methods of breast cancer treatment in depth, and discuss environment and diet as risk factors for the disease. Breast Cancer: Molecular Genetics, Pathogenesis, and Therapeutics constitutes an excellent reference and resource for all those clinical and experimental oncologists, as well as genetic counselors nurses, who need to understand the latest developments in breast cancer biology, risk, and treatment.
Provides a comprehensive description of mass spectrometry basics, applications, and perspectives Mass spectrometry is a modern analytical technique, allowing for fast and ultrasensitive detection and identification of chemical species. It can serve for analysis of narcotics, counterfeit medicines, components of explosives, but also in clinical chemistry, forensic research and anti-doping analysis, for identification of clinically relevant molecules as biomarkers of various diseases. This book describes everything readers need to know about mass spectrometry—from the instrumentation to the theory and applications. It looks at all aspects of mass spectrometry, including inorganic, organic, f...
This book contains the proceedings of the symposium on Microbial Adhesion and Invasion. The meeting was the fifth in a series of symposia initiated and sponsored by the Department of Biochemistry, University of Alabama at Birmingham. We gratefully acknowledge the generous financial support of the following institutions and companies. -Department of Biochemistry, University of Alabama at Birmingham, Birmingham, Alabama, USA - National Institutes of Health, Bethesda, Maryland, USA -Alfa Laval International, AB, Tumba, Sweden -Procter and Gamble, Cincinnati, Ohio, USA -Amgen Inc., Thousand Oaks, California, USA -Johnson and Johnson, New Brunswick, New Jersey, USA We would like to express our appreciation to Agneta Hook, Timo Kostiainen, Mary Homonylo McGavin, Martin McGavin, Cindy Patti, Joe Patti and Anna-Marja Saamanen for their time and hard work making this symposium a success; and special thanks to Kay Cooper and Wade Butcher for help with the management of the symposium and editorial assistance with this book.
The second edition of Neuroimmune Pharmacology bridges the disciplines of neuroscience, immunology and pharmacology from the molecular to clinical levels with particular thought made to engage new research directives and clinical modalities. Bringing together the foremost field authorities from around the world, Neuroimmune Pharmacology will serve as an invaluable resource for the basic and applied scientists of the current decade and beyond.