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Advances in anti-cancer chemotherapy over recent years have led to improved efficacy in curing or controlling many cancers. Some chemotherapy-related side-effects are well recognized and include: nausea, vomiting, bone marrow suppression, peripheral neuropathy, cardiac and skeletal muscle dysfunction and renal impairment. However, it is becoming clearer that some chemotherapy-related adverse effects may persist even in long term cancer survivors. Problems such as cognitive, cardiovascular and gastrointestinal dysfunction, and neuropathy may lead to substantial long term morbidity. Despite improvements in treatments to counteract acute chemotherapy-induced adverse effects, they are often incompletely effective. Furthermore, counter-measures for some acute side-effects and many potential longer term sequelae of anti-cancer chemotherapy have not been developed. Thus, new insights into prevalence and mechanisms of cancer chemotherapy-related side effects are needed and new approaches to improving tolerance and reduce sequelae of cancer chemotherapy are urgently needed. The present Research Topic focuses on adverse effects and sequelae of chemotherapy and strategies to counteract them.
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Dr. Tack receives financial support from Shire, Sofar and Tsumura. The other Topic Editors declare no competing interests with regards to the Research Topic theme.
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Natural Molecules in Neuroprotection and Neurotoxicity brings together research in the area of natural compounds and their dual effects of neuroprotection and neurotoxicity when interacting with brain cells. This book is organized into four sections that address molecular mechanism underlying neuroprotection and neurotoxicity, neuroprotection mediated by natural molecules, neurotoxicity induced by natural compounds and nanotechnology-related strategies utilized in neuroprotection. Written by well-known researchers all over the world, chapters provide an in-depth analysis of numerous molecules, such as algae, plant and fungus-derived molecules, and comprehensively discuss their mechanisms of ...
Coffee in Health and Disease Prevention, Second Edition, presents a comprehensive look at the compounds in coffee, their benefits (or adverse effects), and explores coffee as it relates to specific health conditions. Embracing a holistic approach, this book covers the coffee plant, coffee production and processing, the major varieties of coffee, and its nutritional and compositional properties. Coffee's impact on human health, disease risk, and prevention comprises the majority of the text. Diseases covered including Alzheimer's, anxiety and depression, asthma, diabetes, cancer, and more. This book also covers coffee's impact on organs and organ systems, including the cardiovascular system, ...
Two IBS experts—a New York Times bestselling author and a renowned GI psychologist—offer a groundbreaking, holistic approach with the most updated research to treating and thriving with IBS. IBS affects 45 million Americans; it's also a tricky disease–hard to diagnose, miserable to live with. With the advent of the low FODMAP diet, nutrition is one of the primary treatments--but most folks don't know how to connect the dots between our brain and our gut health. Enter world‑renowned digestive health specialist and registered dietitian Kate Scarlata, and prominent GI psychologist Dr. Megan Riehl; their new book provides a comprehensive, holistic approach to IBS. Mind Your Gut shares...
A Comprehensive Overview of Irritable Bowel Syndrome: Clinical and Basic Science Aspects presents up-to-date knowledge in the field and provides a comprehensive summary of this area of study, including an overview on IBS, starting from its pathogenesis, including genetic, microbial and physiological background, through symptom recognition, diagnosis and IBS treatment, both non-pharmacological and pharmacological. - Compiles the most recent and comprehensive findings in pharmacological targets - Highlights the role of extrinsic and intrinsic factors involved in disease development - Written by leading researchers in the field of Irritable Bowel Syndrome to address research challenges in the field - Includes bonus information on symptom recognition and diagnosis
How do certain medical conditions impact counseling needs? Dr. Charles Hodges and a team of contributing physicians set out to answer some of those questions and offer solid biblical principles for counseling those with medical issues.