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Obesity Epidemiology, Pathogenesis, and Treatment
The book provides a comprehensive perspective on the subject of obesity epidemiology, pathophysiology, and management of obesity. The chapters provide a better understanding of obesity and obesity-related diseases and offer an integrative framework for individualized dietary and exercise programs, behavior modification, pharmaceutical approaches, surgery, and population interventions to reduce the growing epidemic of obesity.
Can the Obesity Crisis Be Reversed?
How can we work together to understand the rise of obesity and reverse its related diseases and societal impacts? Obesity is a complex condition that increases a person's risk for developing diabetes, heart disease, cancer, dementia, and other life-threatening conditions. Contrary to prevailing notions that it results solely from a person's diet and exercise failings, a predisposition to obesity is actually determined by genetics as well as by environmental and socioeconomic factors that lie beyond individual control. In Can the Obesity Crisis Be Reversed?, Dr. Rexford Ahima draws on his extensive laboratory and clinical experiences at top institutions to examine the complicated causes of ob...
Childhood Obesity
The prevalence of childhood overweight and obesity has increased worldwide in recent decades. Obesity in childhood is associated with a wide range of serious health complications and an increased risk of premature illness and death later in life. This book presents childhood obesity trends across multiple demographics and discusses the contributing genetic and environmental factors. It demonstrates the adverse health consequences of childhood obesity both as they relate to childhood and as they last into adulthood and presents multiple methods for obesity treatment included community and family-based intervention, pharmacotherapy, and surgical procedures.
Metabolic Basis of Obesity
The obesity epidemic has generated immense interest in recent years due to the wide-ranging and significant adverse health and economic consequences that surround the problem. Much attention has been focused on behaviors that lead to obesity, in particular to over consumption of energy-dense food and to sedentary lifestyle. However, obesity is an extremely complex condition with poorly defined pathogenesis. Thanks to greatly enhanced research in the area, the discovery of pathways in the brain and peripheral organs that mediate energy homeostasis has provided a framework for understanding the biological basis of obesity. Metabolic Basis of Obesity adds an important new dimension to the growi...
Why Are Health Disparities Everyone's Problem?
How can we all work together to eliminate the avoidable injustices that plague our health care system and society? Health is determined by far more than a person's choices and behaviors. Social and political conditions, economic forces, physical environments, institutional policies, health care system features, social relationships, risk behaviors, and genetic predispositions all contribute to physical and mental well-being. In America and around the world, many of these factors are derived from a lingering history of unequal opportunities and unjust treatment for people of color and other vulnerable communities. But they aren't the only ones who suffer because of these disparities—everyon...
Obesity and Metabolism
It has become increasingly difficult to keep up with the growing body of literature on the genetics, metabolic phenotype and treatment of obesity. This volume brings together an array of chapters from many of the foremost authorities and researchers in this area. Key advances in the genetics of obesity are summarized and the effects of obesity in pregnancy, childhood and old age explored. By scrutinizing the hormones and enzymes most recently implicated in the development, maintenance and consequences of obesity, the biochemical and physiological background of the abnormal metabolism of obesity is mapped out. Furthermore, a practical update on clinical approach and treatment of obesity is offered. Finally, the social aspects of obesity and the view of the obese body in art throughout the centuries are reflected. A valuable overview of causes, metabolic disturbances and treatment options, this volume will appeal to those with an interest in clinical as well as pathophysiological and genetic aspects of obesity. Furthermore, it will provide useful reading for scientists and students who would like to broaden and update their knowledge in this area.
Adrenal in Toxicology
The adrenal gland is vitally important to health and secretes hormones that control many bodily processes ranging from normal metabolism to the response to stressful circumstances. The corticosteroid hormones are the basis for anti-inflammatory medicines and are very widely prescribed. Changes in the function of the adrenal gland, either naturally through stress or disease, or through the action of drugs and chemicals, can have a major impact on the body.; This text focuses on adrenal toxicity, examining how drugs and chemicals can directly and indirectly affect this gland. Coverage includes: classification of the types of adrenal and endocrine toxicity; the mechanistic and molecular basis of toxicity; reasons why the adrenal is the most common target organ in the endocrine system; drug toxicity specific to patients with adrenal disorders; drug- corticosteroid interactions; adverse drug reactions; and how the adrenal gland is vital in tolerance to toxic insult.
Biology of the Lysosome
Updates the understanding of the biological and physiological role of the lysosomal system, furthering the effort to systemize the voluminous information being generated by research. The core section of the 12 review papers consider lysosome metabolism; other sections describe how the lysosome compo
Obesity Epidemiology, Pathogenesis, and Treatment
This title includes a number of Open Access chapters.The book provides a comprehensive perspective on the subject of obesity epidemiology, pathophysiology, and management of obesity. The chapters provide a better understanding of obesity and obesity-related diseases and offer an integrative framework for individualized dietary and exercise programs
Nitric Oxide and the Kidney
A number of remarkable recent breakthroughs have made the study of nitric oxide one of the most exciting fields in physiology and pathophysiology. This authoritative edited volume reviews the progress to date and opens perspectives to novel diagnostic and therapeutic strategies. The contributors are leading authorites, in most cases the investigators who have pioneered the ideas explored in the book.
