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Mood disorders affect around 1 in 5 people, but the diagnosis and management of these conditions can be challenging. This practical handbook presents a comprehensive overview of these disorders, as well as detailed guidelines for their treatment. The handbook takes a transdisciplinary approach to mood disorders, focusing not only on the biological aspects but also on psychosocial features of importance for optimal diagnosis and management. Content covers nosological considerations, historical aspects, peculiarities along the lifespan, and the associations between mood disorders and other conditions, with a focus on their implications for the optimal management of patients. Practical and evidence-based information is discussed on the role of guidelines related to treatment in selected population groups, including youth, the elderly, and women. With a practical, reader-friendly approach, this book will be invaluable for mental health professionals involved in the treatment of patients with mood disorders, including trainees from different mental health areas.
Perinatal psychiatry is an emerging field that investigates the role of perinatal events – for example pregnancy complications and infections – in the development of neuropsychiatric conditions, such as schizophrenia and mood disorders. Among the implicated pathological mechanisms, perinatal-induced inflammation seems to play a major role and is being considered as a potential target for therapeutic intervention. Bringing together various approaches in the field (preclinical and clinical, epidemiological, immunological and genetic methods), the book discusses the available evidence, the putative mechanisms and the challenges ahead.
This book presents the ‘state of the art’ of biomarkers research in neuropsychiatric conditions, from dementia to eating disorders, as well as providing methodological, practical and ethical issues related to the development of biomarkers. Biomarkers have revolutionized clinical research and practice in most fields of medicine, but psychiatry has lagged behind. However, in the last decade, there has been a growing expectation that biomarkers will advance and, ultimately, reframe psychiatry research and practice. Biomarkers might inform about diagnosis, therapeutics, prognosis, contributing to a ‘personalized medicine’. Understanding their meaning, possibilities and limitations will help clinicians, researchers and students in the related areas navigate and excel in the challenging and ever changing field of neuropsychiatric disorders.
This book assembles and presents the available data on the immune/inflammatory dysfunction in psychiatric disorders, indicating the potential of immune mechanisms as either biomarkers or therapeutic targets, as well as discussing the challenges ahead of incorporating this knowledge into clinical practice.
In this issue of Psychiatric Clinics, guest editors Drs. Manish K. Jha and Madhukar H. Trivedi bring their considerable expertise to the topic of Treatment-Resistant Depression. Treatment-resistant depression (TRD), when patients experience an inadequate response to standard treatment plans, is a relatively common occurrence in clinical practice. In this issue, top experts shed light on this difficult-to-treat disorder, helping healthcare professionals improve outcomes for their patients with TRD. - Contains 15 practice-oriented topics including overview of TRD; improving depression outcomes through measurement-based care; approach to diagnosis and treatment for difficult-to-treat depression...
Timely and authoritative, this unique volume focuses on neurocognitive aspects of depression and their implications for assessment, evaluation, clinical management, and research. Experts in the field explore the impact of depression on executive function, learning and memory, working memory, and other critical capacities, and present cutting-edge assessment tools and procedures. The neurocognitive effects of widely used antidepressant treatments are reviewed, from psychotropic medications and evidence-based psychotherapies to established and emerging neuromodulation technologies. Practical aspects of working with adults across the lifespan with depression are addressed, including ways to strengthen treatment engagement and adherence, and to incorporate cultural considerations.
Over the past decade, neuroproteomics has shed light on the molecular features of schizophrenia by depicting biological processes involved with its establishment, maintenance and treatment. These studies have also pointed to potential biomarkers applicable to diagnosis and medication monitoring. Edited by a leader in the field of neuroproteomics with contributions from subject experts, this new volume will address recent findings and compile evidence from difference perspectives—such as human samples, animal models, pluripotent stem cell-derived in vitro pre-clinical models—and provide findings to inform the development of innovative future treatment strategies. This volume will be useful for a broad audience of researchers and professionals, including biologists, neurologists, psychiatrists, analytical chemists, and pharmacists, among others.
Calming the Bipolar Storm:A Guide for Patients and Their Families is for people with bipolar disorder, and anyone who loves or cares for them. This work captures the rapidly advancing research and treatment strategies in the field of bipolar disorders. Discussing causes, presentation, onset, course, and treatments, the book encourages bipolar persons to set a healthy baseline, outlining five areas that promote good overall health in support of their particular circumstances: diet, exercise, sleep, avoiding substance misuse, and finding social support. In this context, Robert G. Fawcett discusses specific medications and their side effects, offering comparisons among them where possible. He d...
This book provides a comprehensive and in-depth discussion on the development of herbicide resistance during the past 50 years, emphasizing the biochemical pathways of herbicide resistance in weeds. It discusses the principles of plant genetics, different methods of genetic engineering, makingof transgenic plants, various transgenic crops conferred with herbicide resistance, evolution of weed, problems subsequent to growing of transgenic crops, benefits and risks of growing transgenic crops, and management of transgenic crops. Packed with up-to-date information, the book includes relevant references, data, figures, and illustrations.