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Interdisciplinary Computing in Java Programming
Books on computation in the marketplace tend to discuss the topics within specific fields. Many computational algorithms, however, share common roots. Great advantages emerge if numerical methodologies break the boundaries and find their uses across disciplines. Interdisciplinary Computing In Java Programming Language introduces readers of different backgrounds to the beauty of the selected algorithms. Serious quantitative researchers, writing customized codes for computation, enjoy cracking source codes as opposed to the black-box approach. Most C and Fortran programs, despite being slightly faster in program execution, lack built-in support for plotting and graphical user interface. This book selects Java as the platform where source codes are developed and applications are run, helping readers/users best appreciate the fun of computation. Interdisciplinary Computing In Java Programming Language is designed to meet the needs of a professional audience composed of practitioners and researchers in science and technology. This book is also suitable for senior undergraduate and graduate-level students in computer science, as a secondary text.
Interdisciplinary Computing in Java Programming
Books on computation in the marketplace tend to discuss the topics within specific fields. Many computational algorithms, however, share common roots. Great advantages emerge if numerical methodologies break the boundaries and find their uses across disciplines. Interdisciplinary Computing In Java Programming Language introduces readers of different backgrounds to the beauty of the selected algorithms. Serious quantitative researchers, writing customized codes for computation, enjoy cracking source codes as opposed to the black-box approach. Most C and Fortran programs, despite being slightly faster in program execution, lack built-in support for plotting and graphical user interface. This book selects Java as the platform where source codes are developed and applications are run, helping readers/users best appreciate the fun of computation. Interdisciplinary Computing In Java Programming Language is designed to meet the needs of a professional audience composed of practitioners and researchers in science and technology. This book is also suitable for senior undergraduate and graduate-level students in computer science, as a secondary text.
Statistical Methods for Drug Safety
Explore Important Tools for High-Quality Work in Pharmaceutical SafetyStatistical Methods for Drug Safety presents a wide variety of statistical approaches for analyzing pharmacoepidemiologic data. It covers both commonly used techniques, such as proportional reporting ratios for the analysis of spontaneous adverse event reports, and newer approach
Patient-Reported Outcomes
Advancing the development, validation, and use of patient-reported outcome (PRO) measures, Patient-Reported Outcomes: Measurement, Implementation and Interpretation helps readers develop and enrich their understanding of PRO methodology, particularly from a quantitative perspective. Designed for biopharmaceutical researchers and others in the health sciences community, it provides an up-to-date volume on conceptual and analytical issues of PRO measures. The book discusses key concepts relating to the measurement, implementation, and interpretation of PRO measures. It covers both introductory and advanced psychometric and biostatistical methods for constructing and analyzing PRO measures. The...
Mixed Effects Models for the Population Approach
Wide-Ranging Coverage of Parametric Modeling in Linear and Nonlinear Mixed Effects Models Mixed Effects Models for the Population Approach: Models, Tasks, Methods and Tools presents a rigorous framework for describing, implementing, and using mixed effects models. With these models, readers can perform parameter estimation and modeling across a whole population of individuals at the same time. Easy-to-Use Techniques and Tools for Real-World Data Modeling The book first shows how the framework allows model representation for different data types, including continuous, categorical, count, and time-to-event data. This leads to the use of generic methods, such as the stochastic approximation of ...
Adaptive Design Theory and Implementation Using SAS and R
Get Up to Speed on Many Types of Adaptive DesignsSince the publication of the first edition, there have been remarkable advances in the methodology and application of adaptive trials. Incorporating many of these new developments, Adaptive Design Theory and Implementation Using SAS and R, Second Edition offers a detailed framework to understand the
Modern Adaptive Randomized Clinical Trials
Is adaptive randomization always better than traditional fixed-schedule randomization? Which procedures should be used and under which circumstances? What special considerations are required for adaptive randomized trials? What kind of statistical inference should be used to achieve valid and unbiased treatment comparisons following adaptive random
Introductory Adaptive Trial Designs
All the Essentials to Start Using Adaptive Designs in No TimeCompared to traditional clinical trial designs, adaptive designs often lead to increased success rates in drug development at reduced costs and time. Introductory Adaptive Trial Designs: A Practical Guide with R motivates newcomers to quickly and easily grasp the essence of adaptive desig
Modeling to Inform Infectious Disease Control
Effectively Assess Intervention Options for Controlling Infectious DiseasesOur experiences with the human immunodeficiency virus (HIV), severe acute respiratory syndrome (SARS), and Ebola virus disease (EVD) remind us of the continuing need to be vigilant against the emergence of new infectious diseases. Mathematical modeling is increasingly used i
Noninferiority Testing in Clinical Trials
Take Your NI Trial to the Next Level Reflecting the vast research on noninferiority (NI) designs from the past 15 years, Noninferiority Testing in Clinical Trials: Issues and Challenges explains how to choose the NI margin as a small fraction of the therapeutic effect of the active control in a clinical trial. Requiring no prior knowledge of NI testing, the book is easily accessible to both statisticians and nonstatisticians involved in drug development. With over 20 years of experience in this area, the author introduces the basic elements of the NI trials one at a time in a logical order. He discusses issues with estimating the effect size based on historical placebo control trials of the active control. The book covers fundamental concepts related to NI trials, such as assay sensitivity, constancy assumption, discounting, and preservation. It also describes patient populations, three-arm trials, and the equivalence of three or more groups.
