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The newer research areas in pharmaceutical sciences, particularly molecular modeling and simulations, prompted a more efficient drug discovery process. Informatics integrated with pharmaceutical sciences (cheminformatics and bioinformatics) became an essential component of drug research. Drug informatics such as genomics and proteomics assists in the Rational Drug Design (RDD). This emerging discipline is known as “Computer-Aided Drug Design (CADD)”, which has profound application in rational drug design (RDD). The advanced and adequate practice in drug design informatics is essential for pharmacy graduates. Hence, a companion for acquiring knowledge on these concepts is vital. The stude...
The continuous effort to perform a more sustainable chemistry has led to the development of new materials that accomplish the principles of green chemistry. In this context, deep eutectic solvents (DESs) have arisen as a new generation of solvents that respond well to most of the characteristics that an ideal green solvent must possess: they are easy and cheap to prepare, stable, easy to handle (they show chemical stability, non-flammability and conductivity), separable from the reaction products, biodegradable and safe for both humans and the environment. At the same time, they show chemical-physical properties similar to ionic liquids, such as low volatility, conductivity and high solvent ...
This book discusses the application of machine learning in genomics. Machine Learning offers ample opportunities for Big Data to be assimilated and comprehended effectively using different frameworks. Stratification, diagnosis, classification and survival predictions encompass the different health care regimes representing unique challenges for data pre-processing, model training, refinement of the systems with clinical implications. The book discusses different models for in-depth analysis of different conditions. Machine Learning techniques have revolutionized genomic analysis. Different chapters of the book describe the role of Artificial Intelligence in clinical and genomic diagnostics. ...
The modern medicinal chemistry utilizes several novel drug discovery tools to identify the drug-like molecules (lead) and to convert them into therapeutically potential molecules. The advanced and adequate practice in synthetic medicinal chemistry is essential for pharmacy graduates (B. Pharmacy and M. Pharmacy) to receive recognition in academia and industry sectors. This book titled Experimental Organic and Medicinal Chemistry-Principles & Practice consists of several topics covering both theory and practical concepts. The material spreads into synthetic and analytical approaches. The synthetic approach includes synthesis of drugs and drug intermediates and green synthetic strategy. The an...
Advances in Computing, Communication, Automation and Biomedical Technology aims to bring together leading academic, scientists, researchers, industry representatives, postdoctoral fellows and research scholars around the world to share their knowledge and research expertise, to advances in the areas of Computing, Communication, Electrical, Civil, Mechanical and Biomedical Systems as well as to create a prospective collaboration and networking on various areas. It also provides a premier interdisciplinary platform for researchers, practitioners, and educators to present and discuss the most recent innovations, trends, and concerns as well as practical challenges encountered, and solutions adopted in the fields of innovation.
The WHO estimates that by 2050, 30% of the world's population will be elderly. The increased life expectancy of the population coupled with falling fertility contributes to this scenario in many countries. Although the life expectancy of the population has increased, the recurring concern is to ensure the quality of life of this group. Some diseases are directly associated with the aging process, such as sarcopenia and osteoporosis. On the other hand, chronic degenerative diseases, such as diabetes, hypertension, and cancer, are associated with long-term inadequate health habits and, therefore, are more prevalent in the elderly. Among the factors that contribute to a lifestyle that influences the onset of these diseases, we can highlight sedentarism and poor diet quality.
“Green gold” or “Poor Man’s Timber” are commonly used terms for bamboo that is a valuable and renewable resource of the world, and has always been an elemental part of human beings in terms of social and economic value. Bamboo is considered a multipurpose plant and has a prolonged history as an adaptable and extensively used renewable resource in conventional and commercial applications. Therefore, the annual demands for bamboos have already out-crossed the annual yields across the world. And the current scenario has forced scientists to pay more attention to the utilization of biotechnological tools for better understanding and improving bamboos. The book provides an overview of t...
The Printed Edition of the Lions District 324B1 for 2015-16, was released in October 2015 by Lions District Governor MJF G Suresh Kumar. This is the Digital Edition of the Printed Directory for viewing in the Smart Phones, Tablets, IPads and Digital Devices.