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Regulation of Ubiquitination and Sumoylation Signaling in Disease
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The Spring and Autumn Annals of Master Yan
The Spring and Autumn Annals of Master Yan is the biography of the most important statesmen and political thinkers of the Eastern Zhou dynasty China: Yan Ying (d. 500 BCE). Living through an exceptionally troubled period, he served three rulers and two dictators of the state of Qi, in Shandong Province. His experiences informed his revolutionary theories concerning the relationship between the individual and the state. Long considered to be a forgery, recent archaeological discoveries have proved the Spring and Autumn Annals of Master Yan to be a genuinely ancient text. This book provides not only the first complete translation of the text into any Western language, but a detailed analysis of the context in which it was produced.
Novel Immune Markers and Predictive Models for Immunotherapy and Prognosis in Breast and Gynecological Cancers
Precision medicine is an emerging practice by which clinicians aim to deliver a personalized treatment program to affected patients based on information gained from their individual clinical and biological profiles. In the context of precise cancer immunotherapy, multi-omics, high-throughput sequencing, big data, and other approaches serve to screen new predictive factors for immunotherapy response and prognosis in cancer patients.
Thiamine
Thiamine: Catalytic Mechanisms in Normal and Disease States brings together the most recent developments in thiamine diphosphate (TDP)-requiring enzyme research and details the mechanisms of catalysis and structure-function relationships, as well as pathophysiological aspects of a spectrum of diseases associated with TDP-requiring enzymes. Providing new insights into neurogenerative diseases, this volume associates defects in the function of TDP-dependent enzymes with numerous metabolic disorders and disease states and offers novel aspects of thiamine enzymes in chiral synthesis as well as new perspectives on the cellular role of thiamine triphosphate and thiamine triphosphates.
Progress in Nucleic Acid Research and Molecular Biology
This is a cumulative subject index for volumes 40-72 of Progress in Nucleic Acid Research and Molecular Biology. This series is intended to bring to light the most recent advances in these overlapping disciplines with a timely compilation of reviews comprising each volume. - Cumulative subject index for volumes 40-72 of Progress in Nucleic Acid Research and Molecular Biology. - Brings to light the most recent advances in these overlapping disciplines with a timely compilation of reviews comprising each volume.
Women and Their Warlords
Explores the complex history and legacy of elite wives, concubines, and daughters of warlords in twentieth-century China. In Women and Their Warlords, historian Kate Merkel-Hess examines the lives and personalities of the female relatives of the military rulers who governed regions of China from 1916 to 1949. Posing for candid photographs and sitting for interviews, these women did not merely advance male rulers’ agendas. They advocated for social and political changes, gave voice to feminist ideas, and shaped how the public perceived them. As the first publicly political partners in modern China, the wives and concubines of Republican-era warlords changed how people viewed elite women’s engagement in politics. Drawing on popular media sources, including magazine profiles and gossip column items, Merkel-Hess draws unexpected connections between militarism, domestic life, and state power in this insightful new account of gender and authority in twentieth-century China.
Interventional Psychiatry
Recent advances in pharmacology and brain stimulation have led to the development of novel treatments for psychiatric disorders. These new advances have led to the development of a new subspeciality, Interventional Psychiatry. Interventional Psychiatry: Road to Novel Therapeutics reviews all specialized treatments including device-based interventions such as electroconvulsive therapy (ECT), repetitive transcranial magnetic stimulation (rTMS), and deep brain stimulation (DBS). This book discusses the procedure-based pharmacologic interventions including ketamine infusion therapy and psychedelic therapies. Internationally contributed, each this book outlines the state of the field, as well as implications for training and the role of the interventional psychiatrist in treatment teams. - Introduces an innovative approach combining both well-established and innovative methodologies - Includes an in-depth description of putative mechanisms of action - Features clinician-friendly presentation of indications, contraindications, and techniques - Outlines guidelines to foster fellowships in Interventional Psychiatry
