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There is a critical need for iron intake during the first period of life. The growing infant requires iron to synthesize hemoglobin and to supply expanding tissues with iron-containing enzymes. A lack of iron will eventually lead to iron deficiency anemia, one of the most common single nutrient deficiencies in the world. Today, detailed information has increased our understanding of iron bioavailability from different dietary sources, uptake mechanisms of iron into the small intestinal mucosa for transport to hepatocytes and erythropoietic cells and subsequent receptor mediated cellular acquisition. Metabolic effects of iron deficiency have also been investigated in several tissues. This comprehensive text integrates recent information and address it from a nutritional perspective. It takes this focus because of the increased knowledge on the interrelationship between iron and other essential nutrients. Specific problems of iron nutriture and oxidant stress in prematurely born infants are also addressed in this informative new text
For the first time, an entire publication has been dedicated to providing a critical review of the identification and analysis of the milk specific proteins such as lactalbumin, lactoferrin and casein; the non-milk specific proteins such as plasma and membrane proteins; and the minor nitrogen-containing components such as enzymes, hormones, and growth factors. Biological roles, whether nutritional, endocrinological or immunological, of the specific nitrogen compounds in mammary milk production and/or growth and development of the breast-fed infant are also presented. Identification of the molecular weight compounds that have led to questions about their function in milk and their inclusion i...
Human milk contains all of the essential nutrients and other functional components thought to have short- and long-term neonatal health benefits, such as positive biological effects on growth, metabolism, cognition, and immunity. This publication brings together the world's experts who touch on the spectrum of current knowledge, from the history and mechanics of breastfeeding, its physiological and clinical effects, to the new surprises revealed by metabolomics and comparative biology. One of the key points made is that human milk is not only a source of essential nutrients, but also contains a variety of bioactive substances. These include essential microbes, long-chain fatty acids, complex oligosaccharides, nucleotides, and bioactive signaling proteins and hormones. This book provides clinicians and researchers with useful insights from multiple perspectives on the various aspects of human milk and lactation.
Research shows that humans respond differently to diets and, moreover, that they display varying predispositions to many diet-dependent metabolic and degenerative diseases. The focus of nutritional science is thus shifting from dietary guidelines for populations to individualized foods and diets. It is the aim of nutrigenomics to assign this human diversity in nutritional response to diet - as well as the subsequent consequences to human health - to specific genetic elements. At the same time, evidence suggests that diet itself is a critical determinant of human diversity. Supplying answers to some crucial issues, as well as identifying directions for further research and practical applications by the food industry, this publication is an important source of information for all those involved in the subject of diet and individual responses.
The present volume is one of a series concerned with topics considered to be of growing interest to those whose ultimate aim is the understanding of the nutrition of man. Volumes on Sweetness, Calcium in Human Biology and Sucrose: Nutritional and Safety Aspects, have already been published, and another, on Dietary Starches and Sugars in Man: A Comparison, is in preparation. Written for workers in the nutritional and allied sciences rather than for the specialist, they aim to fill the gap between the textbook on the one hand and the many publications addressed to the expert on the other. The target readership spans medicine, nutrition and the biological sciences generally and includes those i...
The 11th International Conference on Lymphoid Tissues and Immune Reactions was held in Spa-Liege (Belgium), from 4 to 8 July 1993. The regular devotees refer to these conferences as the "Germinal Centre Conferences or GCC". In the 1960s, the germinal centres were the subject of such considerable study and speculation that a group of dynamic people decided to devote an international conference centered on that topic. This led to the fIrst GCC organized in Bern in 1966. Following the success of this initial meeting, further sessions have been organized at regular intervals and, over the years, the scope of the GCC has been broadened. Nowadays, the GCC conferences are dedicated to in vivo immun...
This informative treatise offers a concise collection of existing, expert data summarizing the composition of milk. The Handbook of Milk Composition summarizes current information on all aspects of human and bovine milk, including: sampling, storage, composition, as well as specific chapters on major and minor components such as protein, carbohydrates, lipids, electrolytes, minerals, vitamins and hormones. The book also features comprehensive coverage of compartmentation, host-defense components, factors affecting composition, composition of commercial formulas, and contaminants.* Reliable data on the composition of human and bovine milks.* Discusses the many factors affecting composition.* Composition tables make up 25-30% of the total book.* Problems concerning sampling and analysis are described.* Should appeal equally to industry and academia.* Also of interest to developing countries in need of information on infant nutrition and agricultural development
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Throughout the developing world, children are suffering from the severe consequences micronutrient deficiencies have on their healthy development. However, early malnutrition is not a problem confined to that part of the world. It may also affect infants born prematurely, children living in poverty and new immigrants to developed countries. Written by leading investigators and clinicians, this publication begins with a review of the epidemiology of micronutrient deficiencies. Further chapters deal with stable isotope methods in research, new etiological aspects such as the impact of micronutrient interactions, bioavailability and infectious diseases, as well as the effects of socio- and geopolitical factors. Another section focuses on the implications of micronutrient deficiencies and psycho-motor development, immune function and bone growth, with regard also to the economic impact. Finally an update on specific strategies to address micronutrient deficiencies is provided. This publication will be of great assistance to pediatricians, clinical investigators, health workers and nutritionists engaged in the prevention and treatment of micronutrient deficiencies.
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