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The second edition of this innovative work again provides a unique perspective on the clinical discovery process by providing input from experts within the NIH on the principles and practice of clinical research. Molecular medicine, genomics, and proteomics have opened vast opportunities for translation of basic science observations to the bedside through clinical research. As an introductory reference it gives clinical investigators in all fields an awareness of the tools required to ensure research protocols are well designed and comply with the rigorous regulatory requirements necessary to maximize the safety of research subjects. Complete with sections on the history of clinical research...
Principles and Practice of Clinical Research, Fourth Edition has been thoroughly revised to provide a comprehensive look at both the fundamental principles and expanding practice of clinical research. New to this edition of this highly regarded reference, authors have focused on examples that broadly reflect clinical research on a global scale while including a discussion of international regulations, studies, and implications. In addition to key topics such as bioethics, clinical outcome data, cultural diversity, protocol guidelines, and "omic platforms, this edition contains new chapters devoted to electronic health records and information resources for clinical researchers, as well as the...
The first edition of Pulmonary Pathology was dedicated to Vascular Diseases. Vasculitis is so complex as to con two giants in the field, Drs. Averill Liebow and Herbert tinue to warrant a separate chapter. Spencer. The current edition is dedicated to all those Each chapter has been updated and revised. Exten who have contributed and are contributing to the field, sive expansion has occurred in Bacterial Infections, Rheumatic Connective Tissue Diseases, Asbestos, those whose individual contributions and queries create its rich fabric. It is our pleasure and honor to summarize Vasculitis, Common Neoplasms, Uncommon Lung the work of many of these individuals. Tumors and Pleural Diseases. Despit...
This critical care medicine book substantially differs from others due to the range of peculiarities that characterize it. Since it deals with acute patients in critical conditions, this is, as it were, a 'borderline'book,in the sense that it is intended for those, who, in their activity, need a continuous and in-depth interdisciplinary approach to optimize the quality of the treatments offered to critically-ill patients. This book helps to have a better understanding of the current limits of human intervention and aims at supplying updated guidelines; in particular, it is intended for those who, although having to guarantee continuity and top-quality therapies, must decide when and why the collaboration with and intervention by experts is necessary.
Each issue lists papers published during the preceding year.
A Sunday Times Book of the Year As featured on the BBC Radio 2 Book Club Dr James Barry: Inspector General of Hospitals, army surgeon, duellist, reformer, ladykiller, eccentric. He performed the first successful Caesarean in the British Empire, outraged the military establishment and gave Florence Nightingale a dressing down at Scutari. At home he was surrounded by a menagerie of animals, including a cat, a goat, a parrot and a terrier. Long ago in Cork, Ireland, he had also been a mother. This is the amazing tale of Margaret Anne Bulkley, the young woman who broke the rules of Georgian society to become one of the most respected surgeons of the century. In an extraordinary life, she crossed paths with the British Empire’s great and good, royalty and rebels, soldiers and slaves. A medical pioneer, she rose to a position that no woman before her had been allowed to occupy, but for all her successes, her long, audacious deception also left her isolated, even costing her the chance to be with the man she loved.