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Mathematical and Computational Oncology
This book constitutes the refereed proceedings of the Second International Symposium on Mathematical and Computational Oncology, ISMCO 2020, which was supposed to be held in San Diego, CA, USA, in October 2020, but was instead held virtually due to the COVID-19 pandemic. The 6 full papers and 4 short papers presented together with 1 invited talk were carefully reviewed and selected from 28 submissions. The papers are organized in topical sections named: statistical and machine learning methods for cancer research; mathematical modeling for cancer research; general cancer computational biology; and posters.
Applications of Dynamical Systems in Biology and Medicine
This volume highlights problems from a range of biological and medical applications that can be interpreted as questions about system behavior or control. Topics include drug resistance in cancer and malaria, biological fluid dynamics, auto-regulation in the kidney, anti-coagulation therapy, evolutionary diversification and photo-transduction. Mathematical techniques used to describe and investigate these biological and medical problems include ordinary, partial and stochastic differentiation equations, hybrid discrete-continuous approaches, as well as 2 and 3D numerical simulation.
Personalized Medicine Meets Artificial Intelligence
The book provides a multidisciplinary outlook on using Artificial Intelligence (AI)-based solutions in the field of Personalized Medicine and its transitioning towards Personalized Digital Medicine. The first section integrates different perspectives on AI-based solutions and highlights their potential in biomedical research and patient care. In the second section, the authors present several real-world examples that demonstrate the successful use of AI technologies in various contexts. These include examples from digital therapeutics, in silico clinical trials, and network pharmacology. In the final section of the book, the authors explore future directions in AI-enhanced biomedical technol...
Systems Biology of Tumor Microenvironment
This edited volume discusses the complexity of tumor microenvironments during cancer development, progression and treatment. Each chapter presents a different mathematical model designed to investigate the interactions between tumor cells and the surrounding stroma and stromal cells. The topics covered in this book include the quantitative image analysis of a tumor microenvironment, the microenvironmental barriers in oxygen and drug delivery to tumors, the development of tumor microenvironmental niches and sanctuaries, intravenous transport of the circulating tumor cells, the role of the tumor microenvironment in chemotherapeutic interventions, the interactions between tumor cells, the extra...
Cálculo
Livro de Cálculo que expõe o conteúdo de forma clara e acessível. Escrito em estilo leve, sem deixar de lado o rigor matemático, o texto é rico em recursos pedagógicos, como figuras, gráficos, exemplos e exercícios. Esta edição apresenta mudanças nas notações, mais explicações nas derivadas, reordenamento e adição de tópicos, tudo com o objetivo de estimular os estudantes a querer ler e aprender mais.
