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Deciphering the T Cell Response in SARS-CoV-2 Infection
COVID-19 is a recently emerged infectious disease caused by the novel coronavirus SARS-CoV-2. The immune system has a primary role in pathogen elimination and a rapid and effective response can limit disease severity. In this context, T cells play the major role in cell mediated adaptive immune response. The protective role of CD4+ and CD8+ T cells has been inferred from studies on patients who recovered from SARS and MERS and accumulating data are now showing their relevance in SARS-CoV-2 infection. Moreover, memory T cells induced by previous pathogens can shape the susceptibility to, and the clinical severity of other infections, but the complete picture has yet to be elucidated. If the virus is not rapidly eliminated, COVID-19 may progress towards a secondary inflammatory phase that is directly responsible for a worsening in clinical symptoms and immune system impairment. Besides marked lymphopenia, COVID-19 patients’ T cell compartment displays several alterations involving different subpopulations of T cells in terms of phenotype, metabolic profile and functionality.
Monitoring Immune Responses in Renal Autoimmune and Autoinflammatory Diseases
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World Congress on Medical Physics and Biomedical Engineering May 26-31, 2012, Beijing, China
The congress’s unique structure represents the two dimensions of technology and medicine: 13 themes on science and medical technologies intersect with five challenging main topics of medicine to create a maximum of synergy and integration of aspects on research, development and application. Each of the congress themes was chaired by two leading experts. The themes address specific topics of medicine and technology that provide multiple and excellent opportunities for exchanges.
SELF-REALIZATION
Author: Dr. LI, JIN WEI, male, was born in Shanghai, China, on February 29, 1956. In terms of education, junior high school graduates whose 10-year education was interrupted due to the impact of the "Great Proletarian Cultural Revolution" in Chinese history from 1966 to 1977 obtained a high school diploma through self-study. From the spring of 1980 to the spring of 1982, he studied in the introductory English course of evening college at Shanghai Foreign Language Institute; In 1984, he passed the examination and was admitted to the Department of History, East China Normal University, one of the famous universities in China, to major in political history. He graduated in 1989 with a diploma a...
Plant Genome Engineering
This volume provides readers with a collection of the latest protocols used to study plant genome editing and trait engineering. The chapters in this book are organized into five parts: genome engineering systems; machinery design and validation; delivery tools; generation and analysis of engineering materials; and crop genome engineering applications. The chapters cover topics such as methods of applying the popular CRISPR-Cas9 or CRISPR-Cas12 systems for editing genomes in different crop species, the use of small synthetic plastome for potato genome engineering, and the use of CRISPR-Cas9 for algal cell genome engineering. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting-edge and comprehensive, Plant Genome Engineering: Methods and Protocols is a valuable tool for researchers interested in learning more about this developing and important field.
Genome editing for precision crop breeding
Comprehensive, systematic review of advances in key CRISPR/Cas technologies, such as TALENS and zinc finger nucleases, double-strand break repair techniques, insertion-based genome edits, base editing, guide RNAs, gRNA/Cas9 constructs and CRISPR/Cas off targeting Covers both techniques and their practical application to particular cereal and other crops Discusses challenges in regulating this emerging technology
Intelligent Robotics and Applications
The 9-volume set LNAI 14267-14275 constitutes the proceedings of the 16th International Conference on Intelligent Robotics and Applications, ICIRA 2023, which took place in Hangzhou, China, during July 5–7, 2023. The 413 papers included in these proceedings were carefully reviewed and selected from 630 submissions. They were organized in topical sections as follows: Part I: Human-Centric Technologies for Seamless Human-Robot Collaboration; Multimodal Collaborative Perception and Fusion; Intelligent Robot Perception in Unknown Environments; Vision-Based Human Robot Interaction and Application. Part II: Vision-Based Human Robot Interaction and Application; Reliable AI on Machine Human Reacti...
I Have No Enemies
Late one night in December 2008, police arrived at the home of Liu Xiaobo—China’s leading dissident, a key figure in the prodemocracy manifesto Charter 08—and took him away. When Liu won the 2010 Nobel Peace Prize as a political prisoner, the award was bestowed on an empty chair. Inside China, the regime sought to erase every trace of his existence. Liu died of liver cancer in 2017 without ever having been allowed to return home. I Have No Enemies is the definitive biography of Liu Xiaobo, offering a meticulously researched account of the twists and turns of a remarkable life. Perry Link and Wu Dazhi explore Liu’s upbringing, immersion in classical Chinese poetry and philosophy, bold...
