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Data Analysis Using Hierarchical Generalized Linear Models with R
Since their introduction, hierarchical generalized linear models (HGLMs) have proven useful in various fields by allowing random effects in regression models. Interest in the topic has grown, and various practical analytical tools have been developed. This book summarizes developments within the field and, using data examples, illustrates how to analyse various kinds of data using R. It provides a likelihood approach to advanced statistical modelling including generalized linear models with random effects, survival analysis and frailty models, multivariate HGLMs, factor and structural equation models, robust modelling of random effects, models including penalty and variable selection and hypothesis testing. This example-driven book is aimed primarily at researchers and graduate students, who wish to perform data modelling beyond the frequentist framework, and especially for those searching for a bridge between Bayesian and frequentist statistics.
Statistical Modelling of Survival Data with Random Effects
This book provides a groundbreaking introduction to the likelihood inference for correlated survival data via the hierarchical (or h-) likelihood in order to obtain the (marginal) likelihood and to address the computational difficulties in inferences and extensions. The approach presented in the book overcomes shortcomings in the traditional likelihood-based methods for clustered survival data such as intractable integration. The text includes technical materials such as derivations and proofs in each chapter, as well as recently developed software programs in R (“frailtyHL”), while the real-world data examples together with an R package, “frailtyHL” in CRAN, provide readers with useful hands-on tools. Reviewing new developments since the introduction of the h-likelihood to survival analysis (methods for interval estimation of the individual frailty and for variable selection of the fixed effects in the general class of frailty models) and guiding future directions, the book is of interest to researchers in medical and genetics fields, graduate students, and PhD (bio) statisticians.
Bayesian Approaches in Oncology Using R and OpenBUGS
Bayesian Approaches in Oncology Using R and OpenBUGS serves two audiences: those who are familiar with the theory and applications of bayesian approach and wish to learn or enhance their skills in R and OpenBUGS, and those who are enrolled in R and OpenBUGS-based course for bayesian approach implementation. For those who have never used R/OpenBUGS, the book begins with a self-contained introduction to R that lays the foundation for later chapters. Many books on the bayesian approach and the statistical analysis are advanced, and many are theoretical. While most of them do cover the objective, the fact remains that data analysis can not be performed without actually doing it, and this means u...
Big Data Analytics in Oncology with R
Big Data Analytics in Oncology with R serves the analytical approaches for big data analysis. There is huge progressed in advanced computation with R. But there are several technical challenges faced to work with big data. These challenges are with computational aspect and work with fastest way to get computational results. Clinical decision through genomic information and survival outcomes are now unavoidable in cutting-edge oncology research. This book is intended to provide a comprehensive text to work with some recent development in the area. Features: Covers gene expression data analysis using R and survival analysis using R Includes bayesian in survival-gene expression analysis Discusses competing-gene expression analysis using R Covers Bayesian on survival with omics data This book is aimed primarily at graduates and researchers studying survival analysis or statistical methods in genetics.
Advanced Regression Models with SAS and R
Advanced Regression Models with SAS and R exposes the reader to the modern world of regression analysis. The material covered by this book consists of regression models that go beyond linear regression, including models for right-skewed, categorical and hierarchical observations. The book presents the theory as well as fully worked-out numerical examples with complete SAS and R codes for each regression. The emphasis is on model accuracy and the interpretation of results. For each regression, the fitted model is presented along with interpretation of estimated regression coefficients and prediction of response for given values of predictors. Features: Presents the theoretical framework for e...
Proceedings of the Pacific Rim Statistical Conference for Production Engineering
This book presents the proceedings of the 2nd Pacific Rim Statistical Conference for Production Engineering: Production Engineering, Big Data and Statistics, which took place at Seoul National University in Seoul, Korea in December, 2016. The papers included discuss a wide range of statistical challenges, methods and applications for big data in production engineering, and introduce recent advances in relevant statistical methods.
Generalized Linear Models with Random Effects
Since their introduction in 1972, generalized linear models (GLMs) have proven useful in the generalization of classical normal models. Presenting methods for fitting GLMs with random effects to data, Generalized Linear Models with Random Effects: Unified Analysis via H-likelihood explores a wide range of applications, including combining information over trials (meta-analysis), analysis of frailty models for survival data, genetic epidemiology, and analysis of spatial and temporal models with correlated errors. Written by pioneering authorities in the field, this reference provides an introduction to various theories and examines likelihood inference and GLMs. The authors show how to extend...
Journal of the American Statistical Association
A scientific and educational journal not only for professional statisticians but also for economists, business executives, research directors, government officials, university professors, and others who are seriously interested in the application of statistical methods to practical problems, in the development of more useful methods, and in the improvement of basic statistical data.
Data Analysis Using Hierarchical Generalized Linear Models with R
Since their introduction, hierarchical generalized linear models (HGLMs) have proven useful in various fields by allowing random effects in regression models. Interest in the topic has grown, and various practical analytical tools have been developed. This book summarizes developments within the field and, using data examples, illustrates how to analyse various kinds of data using R. It provides a likelihood approach to advanced statistical modelling including generalized linear models with random effects, survival analysis and frailty models, multivariate HGLMs, factor and structural equation models, robust modelling of random effects, models including penalty and variable selection and hypothesis testing. This example-driven book is aimed primarily at researchers and graduate students, who wish to perform data modelling beyond the frequentist framework, and especially for those searching for a bridge between Bayesian and frequentist statistics.
