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This first edited Volume on IgY-Technology, addresses the historical and dynamic development of IgY-applications. The authors cover the biological basis and theoretical context, methodological guidance, and applications of IgY-Technology. A focus is laid on the use of IgY-antibodies for prophylactic/therapeutic purposes in human and veterinary medicine. Aside from applications, the chapters also offer an evolutionary understanding of the IgY molecule, IgY receptors and practical prerequisites to produce IgY-antibodies. Guidance is given for every step of the process. Starting with an introduction to hens as a model species and including hen husbandry, hen egg-laying capacity and total IgY ou...
This volume features a collection of papers on emerging concepts, significant insights, novel approaches and ideas in information systems development (ISD). It xamines advances in ISD in general and investigates emerging trends that will shape the ISD research agenda beyond 2020. The book gathers selected papers from the 28th International Conference on Information Systems Development held in Toulon, France on August 28-30, 2019. The revised and extended papers explore the mutual influences between information systems and organizational structures, processes and people, and promote research into methodological issues and ways in which the IS designers and developers are transforming organizations and society through information systems. Chapter "Smart Grid Challenges through the lens of the European General Data Protection Regulation" is available open access under a Creative Commons Attribution 4.0 International License via link.springer.com
This book is the second of two volumes that together offer a comprehensive account of cutting-edge advances in the development of biomaterials for use within tissue engineering and regenerative medicine. In this volume, which is devoted to biomimetic biomaterials, the opening section discusses bone regeneration by means of duck’s feet-derived collagen scaffold and the use of decellularized extracellular matrices. The role of various novel biomimetic hydrogels in regenerative medicine is then considered in detail. The third section focuses on the control of stem cell fate by biomimetic biomaterials, covering exosome-integrated biomaterials for bone regeneration, cellular responses to materi...
Signal transduction comprises the intracellular biochemical signals which induce the appropriate cell response to an external stimulus. The players in signal transduction are diverse, from small molecules as first messengers, to proteins, receptors, transcription factors, among many others. The different signaling pathways and the crosstalk between them originates the unique signaling profile of every cell type in the human body. The cell signaling specificity depends on several aspects including protein composition, subcellular localization and complexes and gene promoters. This textbook provides a comprehensive overview of the specific signaling pathways on a variety of human tissues. This information can be of great value for health science researchers, professionals and students to understand key pathways for tissue-specific functions in the plethora of signals, signals receptors, transducers and effectors. Chapter 3 and 15 are available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.
This is the first comprehensive listing of Amazon fruits from an ethnobotanical perspective. This detailed book covers 50 botanical families, 207 species, in the Amazon including how the people of each region use them. It is lavishly illustrated with high-quality photographs taken by the author, an extensive list of references, and Dr. Smith’s latest, meticulous research. This book should be a foundational work for scholars working in the plant sciences, researchers in ethnobotanical studies, and general interest scholars seeking more detailed information on the latest research by a leading scientist in the Amazon.
This updated second edition of Acute Ischemic Stroke: Imaging and Intervention provides a comprehensive account of the state of the art in the diagnosis and treatment of acute ischemic stroke. The basic format of the first edition has been retained, with sections on fundamentals such as pathophysiology and causes, imaging techniques and interventions. However, each chapter has been revised to reflect the important recent progress in advanced neuroimaging and the use of interventional tools. In addition, a new chapter is included on the classification instruments for ischemic stroke and their use in predicting outcomes and therapeutic triage. All of the authors are internationally recognized experts and members of the interdisciplinary stroke team at the Massachusetts General Hospital and Harvard Medical School. The text is supported by numerous informative illustrations, and ease of reference is ensured through the inclusion of suitable tables. This book will serve as a unique source of up-to-date information for neurologists, emergency physicians, radiologists and other health care providers who care for the patient with acute ischemic stroke.
This open access book presents a comprehensive synthesis of the biodiversity of the oceanic islands of the Gulf of Guinea, a biodiversity hotspot off the west coast of Central Africa. Written by experts, the book compiles data from a plethora of sources – archives, museums, bibliography, official reports and previously unpublished data – to provide readers with the most updated information about the biological richness of these islands and the conservation issues they face. The Gulf of Guinea Oceanic Islands (Príncipe, São Tomé and Annobón and surrounding islets) present extraordinary levels of endemism across different animal, fungi and plant groups. This very high endemism likely r...
The Web is the nervous system of information society. As such, it has a pervasive influence on our daily lives. And yet, in some ways the Web does not have a high MIQ (Machine IQ). What can be done to enhance it? This is the leitmotif of "Intelligent Exploration of the Web," (lEW)--a collection of articles co-edited by Drs. Szczepaniak, Segovia, Kacprzyk and, to a small degree, myself. The articles that comprise lEW address many basic problems ranging from structure analysis of Internet documents and Web dialogue management to intelligent Web agents for extraction of information, and bootstrapping an ontology-based information extraction system. Among the basic problems, one that stands out ...
This guide covers the 2006 World Cup qualifying competition and England's bids to make the finals in Germany. Details of the UEFA Champions League are featured, as well as English and Scottish league/cup games, Nationwide Conference clubs and an invaluable season-by-season who's-who style players directory.
A survey of the state of human freedom around the world investigates such crucial indicators as the status of civil and political liberties and provides individual country reports.