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Emerging Talents in Frontiers in Pharmacology: Gastrointestinal and Hepatic Pharmacology 2022
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Medical Therapy of Ulcerative Colitis
Medical Therapy of Ulcerative Colitis will serve as an invaluable resource for individual physicians use who treat patients with ulcerative colitis. The text presents a comprehensive overview of medical therapy for management of specific clinical scenarios and also a focus on the individual medications used to treat patients with ulcerative colitis. The book will be evidence based and focus on simplifying the current treatment to make it easy to understand. The chapters are written by experts in their fields and provide the most up to date information. This book will target gastroenterologists who focus on IBD, general gastroenterologists, fellows, and surgeons such as colorectal surgeons or GI surgeons who may treat patients with ulcerative colitis.
Autophagy
In recent years strong progress has been made in understanding the molecular basis of Crohn’s disease, a multifactorial chronic inflammatory disease of the gastrointestinal tract. Recent data suggest that if autophagy, the major lysosomal pathway for recycling of cytoplasmic material, is inhibited, this may significantly contribute to an increased susceptibility for Crohn’s disease. Consequently, intense investigations have started to evaluate the potential value of autophagy as a druggable therapeutic target, and as a very necessary diagnostic tool. Interestingly, as well as the promising introduction of direct autophagic modulators, several other drugs already used clinically in the tr...
Molecular Genetics of Inflammatory Bowel Disease
Research in Crohn’s disease (CD) and ulcerative colitis (UC), together known as the inflammatory bowel diseases (IBD), has truly seen a revolution in the last 5-10 years. This book examines how these genetic discoveries have led to the identification of biological functions not previously associated with IBD pathophysiology (e.g. autophagy), how multiple genetic risk factors for IBD converge on given biological functions and that together the identified variants in these genes have predisposing and protective roles (e.g. the multiple variants in the receptor for the IL23 cytokine and its signaling cascade), and how having such a large number of known genetic risk factors has changed our understanding not only about the genetic and molecular overlap between CD and UC, but also between these diseases and other chronic inflammatory diseases (e.g. psoriasis, multiple sclerosis, type 1 diabetes and many others).
Textbook of Clinical Gastroenterology and Hepatology
Whereas other textbooks mix a clinical approach with large amounts of the basic science of gastroenterology, this book concentrates on providing practicing gastroenterologists with 100% clinically focused, evidence-based chapters on how to correctly diagnosis and treat all disorders of the digestive tract. Once again, the book is divided into 4 clear parts: Symptoms, Syndromes and Scenarios; Diseases of the Gut and Liver; Primer of Diagnostic Methods; and Primer of Treatments. An accompanying website contains more than 85 high-definition surgical videos of diagnostic and therapeutic endoscopic procedures, 300 MCQs written to mirror the American College of Gastroenterology postgraduate course exams, more than 35 management protocol charts for different diseases, and 850+ illustrations for use in scientific presentations.
Clinical Dilemmas in Inflammatory Bowel Disease
Evidence-based guidance to answer more than 60 controversial clinical questions on inflammatory bowel disease Clinical Dilemmas in Inflammatory Bowel Disease is a practical handbook providing quick but detailed answers to the questions and challenges that you are faced with daily in the clinical setting. Each short chapter addresses a different topic and provides evidence-based guidance on subjects ranging from optimising current management through to special management problems and novel treatments. This book is suitable for all medical professionals involved in the care of patients with IBD: established and trainee gastroenterologists, colorectal surgeons, pathologists, radiologists, specialist nurses, pharmacists, dieticians and counsellors
Keighley & Williams' Surgery of the Anus, Rectum and Colon, Fourth Edition
This fourth edition of Surgery of the Anus, Rectum and Colon continues to redefine the field, with its comprehensive coverage of common and rare colorectal conditions, advances in the molecular biology and genetics of colorectal diseases, and new laparoscopic techniques. Contributions from international experts on specialized topics and various new illustrations ensure that the extensive text is not only current and authoritative, but easy to understand. No other book provides the expertise of a world-class editorial team with the cutting-edge knowledge you need to master colorectal surgery.
Curbside Consultation in IBD
Are you looking for concise, practical answers to questions that are often left unanswered by traditional IBD references? Are you seeking brief, evidence-based advice for complicated cases or complications? Curbside Consultation in IBD: 49 Clinical Questions provides quick and direct answers to the thorny questions commonly posed during a "curbside consultation" between colleagues. Dr. David Rubin, Dr. Sonia Friedman and Dr. Francis A. Farraye have designed this unique reference, which offers expert advice, preferences, and opinions on tough clinical questions commonly associated with IBD. The unique Q&A format provides quick access to current information related to IBD with the simplicity o...
Autophagy: Cancer, Other Pathologies, Inflammation, Immunity, Infection, and Aging
Understanding the importance and necessity of the role of autophagy in health and disease is vital for the studies of cancer, aging, neurodegeneration, immunology, and infectious diseases. Comprehensive and forward thinking, these books offer a valuable guide to both cellular processes while inciting researchers to explore their potentially important connections. Considering that autophagy is associated with numerous biological processes, including cellular development and differentiation, cancer (both antitumor and protumor functions), immunity, infectious diseases, inflammation, maintenance of homeostasis, response to cellular stress, and degenerative diseases such as Alzheimer's, Parkinso...
The Inflammatory Bowel Disease Yearbook, Vol 3
International specialists review current topics of interest to researchers and clinicians treating Crohn's disease and ulcerative colitis, collectively known as inflammatory bowel disease (IBD). Bernstein (gastroenterology, U. of Manitoba, Winnipeg, Canada) introduces the six chapters' themes of the latest understanding of clinical markers for diag
