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Docência na pandemia
A pandemia proporcionou aos professores diferentes experiências para o enfrentamento dos desafios diários com o fechamento físico de escolas públicas e particulares. Cada um deles precisou encontrar soluções frente às inúmeras realidades e tomar decisões rápidas e responsáveis. Todo esse período trouxe reflexões sobre as ações docentes nos diferentes níveis, da Educação Infantil ao Ensino Superior. A formação continuada também foi lócus de diálogos para se repensar sobre "ser professor" num tempo não esperado, numa situação ainda não vivenciada – a de estar ao mesmo tempo em suas casas para se proteger e permanentemente na ativa pela Educação. Todas essas exper...
Hospital-Based Health Technology Assessment
A timely work describing how localized hospital-based health technology assessment (HB-HTA) complements general, ‘arms-length’ HTA agency efforts, and what has been the collective global impact of HB-HTA across the globe. While HB-HTA has gained significant momentum over the past few years, expertise in the field, and information on the operation and organization of HB-HTA, has been scattered. This book serves to bring this information together to inform those who are currently working in the field of HTA at the hospital, regional, national or global level. In addition, this book is intended for decision-makers and policy-makers with a stake in determining the uptake and decommissioning ...
Clinical Proteomics
This detailed volume explores techniques in clinical proteomics, an emerging discipline aimed at deciphering the molecular mechanisms underlying the progression of diseases and at identifying new biomarkers and therapeutic targets to expand the physicians’ toolbox for precision medicine-based patient care. From sample processing to multi-omics approaches, the book provides straight-forward protocols on a wide array of vital areas of study. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Clinical Proteomics: Methods and Protocols serves as an ideal guide for researchers working to expand upon the knowledge base needed to push forward toward a more personalized version of medicine.
Tissue Proteomics
This book presents a compilation of methods that detail improved protein and peptide sample preparation and identification. Chapters guide readers through methods for depletion of myofibril-associated proteins, peptide sample preparation in urinary proteomics, purification of targeted proteins from native tissues, fractionation strategies for protein analysis, and GeLC-MS as a sample preparation method for sample preparation for proteomics using minimal amount of tissue. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Tissue Proteomics: Methods and Protocols, Second Edition aims to ensure successful results in the further study of this vital field.
Promoting Health, Preventing Disease The Economic Case
A growing body of evidence from economic studies shows areas where appropriate policies can generate health and other benefits at an affordable cost, sometimes reducing health expenditure and helping to redress health inequalities at the same time.
Subcellular Proteomics
This volume summarizes the new developments that made subcellular proteomics a rapidly expanding area. It examines the different levels of subcellular organization and their specific methodologies. In addition, the book includes coverage of systems biology that deals with the integration of the data derived from these different levels to produce a synthetic description of the cell as a system.
The Invisible Cure
In 1993, Helen Epstein, a scientist working with a biotechnology company searching for an AIDS vaccine, moved to Uganda, where she witnessed first-hand the suffering caused by the HIV virus. The Invisible Cure, dramatic, illuminating and beautifully written, recounts the struggle of international health experts, governments and ordinary Africans to understand the devastating spread of HIV in Africa, and traces how their responses to the crisis have changed in light of new medical developments and political realities. The AIDS epidemic in Africa is uniquely severe. It is partly a consequence of the political, social, and economic upheavals of the past century, which have left millions of Afri...
Distribution Ecology
This book brings together a set of approaches to the study of individual-species ecology based on the analysis of spatial variations of abundance. Distribution ecology assumes that ecological phenomena can be understood when analyzing the extrinsic (environmental) or intrinsic (physiological constraints, population mechanisms) that correlate with this spatial variation. Ecological processes depend on geographical scales, so their analysis requires following environmental heterogeneity. At small scales, the effects of biotic factors of ecosystems are strong, while at large scales, abiotic factors such as climate, govern ecological functioning. Responses of organisms also depend on scales: at small scales, adaptations dominate, i.e. the ability of organisms to respond adaptively using habitat decision rules that maximize their fitness; at large scales, limiting traits dominate, i.e., tolerance ranges to environmental conditions.
Distributional Cost-Effectiveness Analysis
Distributional cost-effectiveness analysis aims to help healthcare and public health organizations make fairer decisions with better outcomes. It can provide information about equity in the distribution of costs and effects - who gains, who loses, and by how much - and the trade-offs that sometimes occur between equity and efficiency. This is a practical guide to methods for quantifying the equity impacts of health programmes in high, middle, and low-income countries. The methods can be tailored to analyse different equity concerns in different decision making contexts. The handbook provides both hands-on training for postgraduate students and analysts and an accessible guide for academics, practitioners, managers, policymakers, and stakeholders. Part I is an introduction and overview for research commissioners, users, and producers. Parts II and III provide step-by-step guidance on how to simulate and evaluate distributions, with accompanying spreadsheet training exercises. Part IV concludes with discussions about how to handle uncertainty about facts and disagreement about values, and the future challenges facing this growing field. Book jacket.
Flavour and Fragrance Chemistry
The volume deals with several aspects of the chemistry of both synthetic and natural organic compounds related to flavours and fragrances. It presents very recent results, some of them previously unpublished, and findings related to the chemistry of flavours and fragrances. It is organized in four sections: flavours and fragrances of foodstuffs, essential oils and other natural products from plants, applied aspects of flavour and fragrance production and detection, analytical aspects of flavour and fragrance isolation and identification. It should be of interest to academic and applied scientists in the field of organic chemistry, phytochemistry, analytical chemistry and food science.
